Evaluation of Veterinary-Specific Interpretive Criteria for Susceptibility Testing of Streptococcus equi Subspecies with Trimethoprim-Sulfamethoxazole and Trimethoprim-Sulfadiazine

Antimicrobial susceptibility test results for trimethoprim-sulfadiazine with Streptococcus equi subspecies are interpreted based on human data for trimethoprim-sulfamethoxazole. The veterinary-specific data generated in this study support a single breakpoint for testing trimethoprim-sulfamethoxazole...

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Bibliographic Details
Published in:Journal of clinical microbiology 2017-01, Vol.55 (1), p.326-330
Main Authors: Sadaka, Carmen, Kanellos, Theo, Guardabassi, Luca, Boucher, Joseph, Watts, Jeffrey L
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents - pharmacology
Clinical Veterinary Microbiology
Drug Combinations
Microbial Sensitivity Tests - methods
Microbial Sensitivity Tests - standards
Streptococcus equi
Streptococcus equi - drug effects
Sulfadiazine - pharmacology
Trimethoprim - pharmacology
Trimethoprim, Sulfamethoxazole Drug Combination - pharmacology
Veterinary Medicine - methods
Veterinary Medicine - standards
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Summary:Antimicrobial susceptibility test results for trimethoprim-sulfadiazine with Streptococcus equi subspecies are interpreted based on human data for trimethoprim-sulfamethoxazole. The veterinary-specific data generated in this study support a single breakpoint for testing trimethoprim-sulfamethoxazole and/or trimethoprim-sulfadiazine with S. equi This study indicates trimethoprim-sulfamethoxazole as an acceptable surrogate for trimethoprim-sulfadiazine with S. equi.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.01610-16