D-dimer level for predicting the in-hospital mortality in liver cirrhosis: A retrospective study

• Published in: Experimental and therapeutic medicine 2017-01, Vol.13 (1), p.285-289
• Main Authors: Li, Yun, Qi, Xingshun, Li, Hongyu, Dai, Junna, Deng, Han, Li, Jing, Peng, Ying, Liu, Xu, Sun, Xiaolin, Guo, Xiaozhong
• Format: Article
• Language: English
• Subjects: Alcohol; Analysis; Blood; Child-Pugh; China; D-dimer; Embolisms; Health risk assessment; Hepatitis; Hospitals; Liver cirrhosis; Liver diseases; Model for End-Stage Liver Disease; Mortality; Patient outcomes; Patients; Prognosis; Software; Studies; survival; Thrombosis
• ISSN: 1792-0981; 1792-1015
• DOI: 10.3892/etm.2016.3930

The present study aimed to examine the correlation of D-dimer levels with the Child-Pugh and MELD scores, as well as to determine the predictive ability of D-dimer level for the in-hospital mortality of liver cirrhosis patients. All cirrhotic patients who were consecutively admitted to our hospital between January 2011 and June 2014, and underwent D-dimer tests on admission were retrospectively analyzed. Pearson's χ2 tests were employed to evaluate the correlations of D-dimer levels with Child-Pugh and MELD scores. In addition, receiver operating curve (ROC) analysis was employed to evaluate the specificity and sensitivity of D-dimer levels for predicting the in-hospital mortality. In total, 703 cirrhotic patients were included in the study, with an in-hospital mortality of 5.4% (38/703). The D-dimer levels were correlated with Child-Pugh (correlation coefficient, 0.219; P