Thrombotic microangiopathy: An unusual cause of renal failure in rheumatoid arthritis

Rheumatoid arthritis (RA) is one of the commonest rheumatological diseases. Renal involvement is not common but can occur as a result of chronic inflammation as part of disease process or drug toxicity. Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocy...

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Bibliographic Details
Published in:Indian journal of nephrology 2017-01, Vol.27 (1), p.81-83
Main Authors: Sakthirajan, R, Dhanapriya, J, Dineshkumar, T, Gopalakrishnan, N, Murugan, S, Balasubramaniyan, T
Format: Article
Language:English
Subjects:
Case Report
Case studies
Causes of
Complications and side effects
Kidney failure
Rheumatoid arthritis
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Summary:Rheumatoid arthritis (RA) is one of the commonest rheumatological diseases. Renal involvement is not common but can occur as a result of chronic inflammation as part of disease process or drug toxicity. Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and organ failure of variable severity. Only a few cases of TMA in patients with RA were reported to date. We describe a 45-year-old female patient with RA who presented with oliguria and edema. Renal biopsy showed TMA with patchy cortical necrosis. She improved with hemodialysis and plasmapheresis.
ISSN:0971-4065
1998-3662
DOI:10.4103/0971-4065.179207