Evaluation of hyperdense renal lesions incidentally detected on single-phase post-contrast CT using dual-energy CT

• Published in: British journal of radiology 2016-06, Vol.89 (1062), p.20150860-20150860
• Main Authors: Cha, Dongik, Kim, Chan Kyo, Park, Jung Jae, Park, Byung Kwan
• Format: Article
• Language: English
• Subjects: Adult; Aged; Contrast Media - administration & dosage; Diagnosis, Differential; Genitourinary Tract; Humans; Incidental Findings; Kidney Diseases, Cystic - diagnostic imaging; Kidney Diseases, Cystic - pathology; Kidney Neoplasms - diagnostic imaging; Kidney Neoplasms - pathology; Middle Aged; Observer Variation; Radiography, Dual-Energy Scanned Projection - methods; Reproducibility of Results; Sensitivity and Specificity; Tomography, X-Ray Computed - methods; Young Adult
• ISSN: 0007-1285; 1748-880X
• DOI: 10.1259/bjr.20150860

To investigate the utility of dual-energy CT (DECT) for differentiating between solid and benign cystic lesions presenting as hyperdense renal lesions incidentally detected on single-phase post-contrast CT. 90 hyperdense renal lesions incidentally detected on single-phase post-contrast CT were evaluated with follow-up DECT. DECT protocols included true non-contrast (TNC), DE corticomedullary and DE late nephrographic phase imaging. The CT numbers of hyperdense renal lesions were calculated on linearly blended and iodine overlay (IO) images, and the results were compared. In total, 47 benign cystic and 43 solid renal lesions were analyzed. For differentiating between solid and benign cystic lesions on the two phases, the specificity and accuracy of all lesions and lesions  0.05). DECT may be useful for differentiating between solid and benign cystic lesions presenting as hyperdense renal lesions incidentally detected on single-phase post-contrast CT, particularly with the size ≥1.5 cm. DECT may be used to characterize hyperdense renal lesions ≥1.5 cm incidentally detected on single-phase post-contrast CT, without the use of TNC images.