Flexible Substrate-Based Devices for Point-of-Care Diagnostics

Point-of-care (POC) diagnostics play an important role in delivering healthcare, particularly for clinical management and disease surveillance in both developed and developing countries. Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and ma...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) 2016-11, Vol.34 (11), p.909-921
Main Authors: Wang, ShuQi, Chinnasamy, Thiruppathiraja, Lifson, Mark A, Inci, Fatih, Demirci, Utkan
Format: Article
Language:English
Subjects:
Developing countries
flexible substrate
Glucose
Heat conductivity
Humans
Immunoglobulins
Internal Medicine
Lab-On-A-Chip Devices
Laboratories
LDCs
Microfluidic Analytical Techniques - instrumentation
Monitoring, Physiologic - instrumentation
Physicochemical properties
Plasma etching
Pliability
point-of-care diagnostics
Point-of-Care Systems
Polyethylene terephthalate
polymer
Polymers
Spectrum analysis
Substrates
Textiles
Uric acid
Urine
wearable devices
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Summary:Point-of-care (POC) diagnostics play an important role in delivering healthcare, particularly for clinical management and disease surveillance in both developed and developing countries. Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and mass production capability. Recently, flexible polymer substrates have been investigated due to their enhanced physicochemical properties, potential to be integrated into wearable devices with wireless communications for personalized health monitoring, and ability to be customized for POC diagnostics. Here, we focus on the latest advances in developing flexible substrate-based diagnostic devices, including paper and polymers, and their clinical applications.
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2016.05.009