Relationship between lead exposure and mild cognitive impairment

Since it is still controversial whether-low-to moderate long-term lead below current threshold values causes neurobehavioural deficits in adults. Forty lead-exposed workers subjects with a mean blood lead (PbB) level of 56.4 μg/dL and 40 non-lead-exposed aged matched subjects (PbB: 15.4 μg/dL) with...

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Bibliographic Details
Published in:Journal of preventive medicine and hygiene 2016-12, Vol.57 (4), p.E205-E210
Main Authors: Fenga, C, Gangemi, S, Alibrandi, A, Costa, C, Micali, E
Format: Article
Language:English
Subjects:
Adult
Case-Control Studies
Cognitive Dysfunction - etiology
Humans
Lead - toxicity
Male
Occupational Exposure
Original
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Summary:Since it is still controversial whether-low-to moderate long-term lead below current threshold values causes neurobehavioural deficits in adults. Forty lead-exposed workers subjects with a mean blood lead (PbB) level of 56.4 μg/dL and 40 non-lead-exposed aged matched subjects (PbB: 15.4 μg/dL) with the same socio-economic background were investigated. Participants were administered a neuropsychological tests consisting of BAMT (Branches Alternate Movements Task), FT (Finger Tapping Speed), DS (Digit Span) POMS (Profile of Mood States). Authors noted a significant relationship between the exposed and the referent groups in tests mainly involving executive functions, short time memory and psycho-emotional variables. In addition, Poisson regression test performed on single psychoemotional factors (POMS), has allowed to evidence a significant influence of Pb e ZPP levels on tension, anxiety and depression. The present study showed that lead exposure among adults at levels previously considered safe, results in impairment of certain cognitive abilities.
ISSN:1121-2233
2421-4248