Platelet-to-Lymphocyte Ratio: A Novel Prognostic Factor for Prediction of 90-day Outcomes in Critically Ill Patients With Diabetic Ketoacidosis

Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and the novel systemic inflammation marker platelet-to-lymphocyte ratio (PLR) may be associated with clinical outcome in patients with DKA. This study aimed to investigate the utility of PLR in predicting 90-da...

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Bibliographic Details
Published in:Medicine (Baltimore) 2016-01, Vol.95 (4), p.e2596-e2596
Main Authors: Liu, Wen-Yue, Lin, Shi-Gang, Wang, Li-Ren, Fang, Chen-Chen, Lin, Yi-Qian, Braddock, Martin, Zhu, Gui-Qi, Zhang, Zhongheng, Zheng, Ming-Hua, Shen, Fei-Xia
Format: Article
Language:English
Subjects:
Adult
Aged
Critical Illness
Diabetic Ketoacidosis - blood
Diabetic Ketoacidosis - mortality
Female
Humans
Intensive Care Units
Kaplan-Meier Estimate
Longitudinal Studies
Lymphocyte Count
Male
Middle Aged
Observational Study
Patient Readmission
Platelet Count
Predictive Value of Tests
Prognosis
Retrospective Studies
Time Factors
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Summary:Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and the novel systemic inflammation marker platelet-to-lymphocyte ratio (PLR) may be associated with clinical outcome in patients with DKA. This study aimed to investigate the utility of PLR in predicting 90-day clinical outcomes in patients with DKA. Patient data exacted from the Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II) database was analyzed. A cutoff value for PLR of 267.67 was determined using Youden index (P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000002596