The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM)

The biological processes that come into play during orthodontic tooth movement (OTM) have been shown to be influenced by a variety of pharmacological agents. The effects of such agents are of particular relevance to the clinician as the rate of tooth movement can be accelerated or reduced as a resul...

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Bibliographic Details
Published in:Frontiers in physiology 2017-02, Vol.8, p.67-67
Main Authors: Kouskoura, Thaleia, Katsaros, Christos, von Gunten, Stephan
Format: Article
Language:English
Subjects:
Physiology
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Summary:The biological processes that come into play during orthodontic tooth movement (OTM) have been shown to be influenced by a variety of pharmacological agents. The effects of such agents are of particular relevance to the clinician as the rate of tooth movement can be accelerated or reduced as a result. This review aims to provide an overview of recent insights into drug-mediated effects and the potential use of drugs to influence the rate of tooth movement during orthodontic treatment. The limitations of current experimental models and the need for well-designed clinical and pre-clinical studies are also discussed.
ISSN:1664-042X
1664-042X
DOI:10.3389/fphys.2017.00067