Comparison of multi-modal early oral nutrition for the tolerance of oral nutrition with conventional care after major abdominal surgery: a prospective, randomized, single-blind trial

Early oral nutrition (EON) has been shown to improve recovery of gastrointestinal function, length of stay and mortality after abdominal surgery; however, early oral nutrition often fails during the first week after surgery. Here, a multi-modal early oral nutrition program is introduced to promote r...

Full description

Saved in:
Bibliographic Details
Published in:Nutrition journal 2017-02, Vol.16 (1), p.11-11, Article 11
Main Authors: Sun, Da-Li, Li, Wei-Ming, Li, Shu-Min, Cen, Yun-Yun, Xu, Qing-Wen, Li, Yi-Jun, Sun, Yan-Bo, Qi, Yu-Xing, Lin, Yue-Ying, Yang, Ting, Lu, Qi-Ping, Xu, Peng-Yuan
Format: Article
Language:English
Subjects:
Abdomen
Abdomen - surgery
Abdominal surgery
Aged
Colectomy
Colorectal cancer
Cost-Benefit Analysis
Defecation
Defecation - physiology
Digestive System Surgical Procedures
Endpoint Determination
Enteral nutrition
Female
Gastrectomy
Gastrointestinal surgery
Hospitals
Humans
Length of Stay
Male
Middle Aged
Nutrition
Nutritional Status
Nutritional Support
Parenteral nutrition
Patients
Postoperative Care - methods
Postoperative Complications - prevention & control
Prospective Studies
Sample Size
Single-Blind Method
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Early oral nutrition (EON) has been shown to improve recovery of gastrointestinal function, length of stay and mortality after abdominal surgery; however, early oral nutrition often fails during the first week after surgery. Here, a multi-modal early oral nutrition program is introduced to promote recovery of gastrointestinal function and tolerance of oral nutrition. Consecutive patients scheduled for abdominal surgery were randomized to the multimodal EON group or a group receiving conventional care. The primary endpoint was the time of first defecation. The secondary endpoints were outcomes and the cost-effectiveness ratio in treating infectious complications. The rate of infectious-free patients was regarded as the index of effectiveness. One hundred seven patients were randomly assigned to groups. Baseline characteristics were similar for both groups. In intention-to-treat analysis, the success rate of oral nutrition during the first week after surgery in the multimodal EON group was 44 (83.0%) versus 31 (57.4%) in the conventional care group (P = 0.004). Time to first defecation, time to flatus, recovery time of bowel sounds, and prolonged postoperative ileus were all less in the multimodal EON group (P 
ISSN:1475-2891
1475-2891
DOI:10.1186/s12937-017-0228-7