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Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review
Curcumin, the major curcuminoid of the turmeric, has been extensively used in many countries since ancient time for preventing and/or treating a multitude of diseases. This review is to illustrate the researches on the properties of curcumin and its potential therapeutic efficacy in major anterior s...
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| Published in: | Frontiers in pharmacology 2017-02, Vol.8, p.66-66 |
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| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c396t-ffb180b86419827d79d7bf0bacc960f240d1ee9911ae07f4efc4128745b59cdb3 |
| container_end_page | 66 |
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| container_start_page | 66 |
| container_title | Frontiers in pharmacology |
| container_volume | 8 |
| creator | Liu, Xiu-Fen Hao, Ji-Long Xie, Tian Mukhtar, Nour Jama Zhang, Wiley Malik, Tayyab Hamid Lu, Cheng-Wei Zhou, Dan-Dan |
| description | Curcumin, the major curcuminoid of the turmeric, has been extensively used in many countries since ancient time for preventing and/or treating a multitude of diseases. This review is to illustrate the researches on the properties of curcumin and its potential therapeutic efficacy in major anterior segment eye diseases. The bio-medical potential of curcumin is restricted because of its low solubility and digestive bioavailability. This review will discuss promising research in improving curcumin bioavailability through structural modification.
and
research made progress in studying the beneficial effects of curcumin on major anterior segment eye diseases, including anti-angiogenesis effect in corneal diseases; anti-inflammation or anti-allergy effects in dry eye disease, conjunctivitis, anterior uveitis; anti-proliferation and pro-apoptosis effects in pterygium; anti-oxidative stress, anti-osmotic stress, anti-lipid peroxidation, pro-apoptosis, regulating calcium homeostasis, sequestrating free radicals, protein modification and degradation effects in cataracts; neuroprotective effects in glaucoma. Curcumin exhibited to be a potent therapeutic candidate for treating those anterior segment eye diseases. |
| doi_str_mv | 10.3389/fphar.2017.00066 |
| format | article |
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and
research made progress in studying the beneficial effects of curcumin on major anterior segment eye diseases, including anti-angiogenesis effect in corneal diseases; anti-inflammation or anti-allergy effects in dry eye disease, conjunctivitis, anterior uveitis; anti-proliferation and pro-apoptosis effects in pterygium; anti-oxidative stress, anti-osmotic stress, anti-lipid peroxidation, pro-apoptosis, regulating calcium homeostasis, sequestrating free radicals, protein modification and degradation effects in cataracts; neuroprotective effects in glaucoma. Curcumin exhibited to be a potent therapeutic candidate for treating those anterior segment eye diseases.</description><identifier>ISSN: 1663-9812</identifier><identifier>EISSN: 1663-9812</identifier><identifier>DOI: 10.3389/fphar.2017.00066</identifier><identifier>PMID: 28261099</identifier><language>eng</language><publisher>Switzerland: Frontiers Media S.A</publisher><subject>Pharmacology</subject><ispartof>Frontiers in pharmacology, 2017-02, Vol.8, p.66-66</ispartof><rights>Copyright © 2017 Liu, Hao, Xie, Mukhtar, Zhang, Malik, Lu and Zhou. 2017 Liu, Hao, Xie, Mukhtar, Zhang, Malik, Lu and Zhou</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-ffb180b86419827d79d7bf0bacc960f240d1ee9911ae07f4efc4128745b59cdb3</citedby><cites>FETCH-LOGICAL-c396t-ffb180b86419827d79d7bf0bacc960f240d1ee9911ae07f4efc4128745b59cdb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306202/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306202/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28261099$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Xiu-Fen</creatorcontrib><creatorcontrib>Hao, Ji-Long</creatorcontrib><creatorcontrib>Xie, Tian</creatorcontrib><creatorcontrib>Mukhtar, Nour Jama</creatorcontrib><creatorcontrib>Zhang, Wiley</creatorcontrib><creatorcontrib>Malik, Tayyab Hamid</creatorcontrib><creatorcontrib>Lu, Cheng-Wei</creatorcontrib><creatorcontrib>Zhou, Dan-Dan</creatorcontrib><title>Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review</title><title>Frontiers in pharmacology</title><addtitle>Front Pharmacol</addtitle><description>Curcumin, the major curcuminoid of the turmeric, has been extensively used in many countries since ancient time for preventing and/or treating a multitude of diseases. This review is to illustrate the researches on the properties of curcumin and its potential therapeutic efficacy in major anterior segment eye diseases. The bio-medical potential of curcumin is restricted because of its low solubility and digestive bioavailability. This review will discuss promising research in improving curcumin bioavailability through structural modification.
and
research made progress in studying the beneficial effects of curcumin on major anterior segment eye diseases, including anti-angiogenesis effect in corneal diseases; anti-inflammation or anti-allergy effects in dry eye disease, conjunctivitis, anterior uveitis; anti-proliferation and pro-apoptosis effects in pterygium; anti-oxidative stress, anti-osmotic stress, anti-lipid peroxidation, pro-apoptosis, regulating calcium homeostasis, sequestrating free radicals, protein modification and degradation effects in cataracts; neuroprotective effects in glaucoma. Curcumin exhibited to be a potent therapeutic candidate for treating those anterior segment eye diseases.</description><subject>Pharmacology</subject><issn>1663-9812</issn><issn>1663-9812</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpVkUtLAzEUhYMoVqp7VzJLF7bmMc0kLoRS6wMERSsuQyZz00bmUZOZiv_e1FbR1T1wzz3nwofQMcFDxoQ8t8uF9kOKSTbEGHO-gw4I52wgBaG7f3QPHYXwFi2YScl4uo96VFBOsJQH6HXSedNVrj5Lxslj00LdOl0mswV4vYSudSaZ6LpwhW4hsY1PxnUL3kXxDPMqupPpJyRXLoAOEC5iyBOsHHwcoj2rywBH29lHL9fT2eR2cP9wczcZ3w8Mk7wdWJsTgXPBUyIFzYpMFlluca6NkRxbmuKCAEhJiAac2RSsSQkVWTrKR9IUOeujy03usssrKEz8yOtSLb2rtP9UjXbq_6Z2CzVvVmrEMKeYxoDTbYBv3jsIrapcMFCWuoamC4rEskwIxtJoxRur8U0IHuxvDcFqjUR9I1FrJOobSTw5-fve78EPAPYFDDSJLw</recordid><startdate>20170214</startdate><enddate>20170214</enddate><creator>Liu, Xiu-Fen</creator><creator>Hao, Ji-Long</creator><creator>Xie, Tian</creator><creator>Mukhtar, Nour Jama</creator><creator>Zhang, Wiley</creator><creator>Malik, Tayyab Hamid</creator><creator>Lu, Cheng-Wei</creator><creator>Zhou, Dan-Dan</creator><general>Frontiers Media S.A</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170214</creationdate><title>Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review</title><author>Liu, Xiu-Fen ; Hao, Ji-Long ; Xie, Tian ; Mukhtar, Nour Jama ; Zhang, Wiley ; Malik, Tayyab Hamid ; Lu, Cheng-Wei ; Zhou, Dan-Dan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-ffb180b86419827d79d7bf0bacc960f240d1ee9911ae07f4efc4128745b59cdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Xiu-Fen</creatorcontrib><creatorcontrib>Hao, Ji-Long</creatorcontrib><creatorcontrib>Xie, Tian</creatorcontrib><creatorcontrib>Mukhtar, Nour Jama</creatorcontrib><creatorcontrib>Zhang, Wiley</creatorcontrib><creatorcontrib>Malik, Tayyab Hamid</creatorcontrib><creatorcontrib>Lu, Cheng-Wei</creatorcontrib><creatorcontrib>Zhou, Dan-Dan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Frontiers in pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Xiu-Fen</au><au>Hao, Ji-Long</au><au>Xie, Tian</au><au>Mukhtar, Nour Jama</au><au>Zhang, Wiley</au><au>Malik, Tayyab Hamid</au><au>Lu, Cheng-Wei</au><au>Zhou, Dan-Dan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review</atitle><jtitle>Frontiers in pharmacology</jtitle><addtitle>Front Pharmacol</addtitle><date>2017-02-14</date><risdate>2017</risdate><volume>8</volume><spage>66</spage><epage>66</epage><pages>66-66</pages><issn>1663-9812</issn><eissn>1663-9812</eissn><abstract>Curcumin, the major curcuminoid of the turmeric, has been extensively used in many countries since ancient time for preventing and/or treating a multitude of diseases. This review is to illustrate the researches on the properties of curcumin and its potential therapeutic efficacy in major anterior segment eye diseases. The bio-medical potential of curcumin is restricted because of its low solubility and digestive bioavailability. This review will discuss promising research in improving curcumin bioavailability through structural modification.
and
research made progress in studying the beneficial effects of curcumin on major anterior segment eye diseases, including anti-angiogenesis effect in corneal diseases; anti-inflammation or anti-allergy effects in dry eye disease, conjunctivitis, anterior uveitis; anti-proliferation and pro-apoptosis effects in pterygium; anti-oxidative stress, anti-osmotic stress, anti-lipid peroxidation, pro-apoptosis, regulating calcium homeostasis, sequestrating free radicals, protein modification and degradation effects in cataracts; neuroprotective effects in glaucoma. Curcumin exhibited to be a potent therapeutic candidate for treating those anterior segment eye diseases.</abstract><cop>Switzerland</cop><pub>Frontiers Media S.A</pub><pmid>28261099</pmid><doi>10.3389/fphar.2017.00066</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Frontiers in pharmacology, 2017-02, Vol.8, p.66-66 |
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| language | eng |
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| source | PubMed |
| subjects | Pharmacology |
| title | Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review |
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