Dual tracer pet imaging (68ga-dotatate and 18f-fdg) features in pulmonary carcinoid: Correlation with tumor proliferation index

Pulmonary carcinoid tumors are rare group of lung neoplasms representing 1% of all the lung tumors. The typical bronchial carcinoids showed higher and more selective uptake of 68Ga-DOTATATE than of 18F-FDG on PET-CT. The Ki-67(MIB-1), a tumor proliferation index is a prognostic marker in neuroendocr...

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Bibliographic Details
Published in:Indian journal of nuclear medicine 2017-01, Vol.32 (1), p.39-41
Main Authors: Bhatkar, Dhiraj, Utpat, Ketaki, Basu, Sandip, Joshi, Jyotsna
Format: Article
Language:English
Subjects:
Care and treatment
Case Report
Lung cancer
Positron emission tomography
Prognosis
Tracers (Biology)
Tumors
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Summary:Pulmonary carcinoid tumors are rare group of lung neoplasms representing 1% of all the lung tumors. The typical bronchial carcinoids showed higher and more selective uptake of 68Ga-DOTATATE than of 18F-FDG on PET-CT. The Ki-67(MIB-1), a tumor proliferation index is a prognostic marker in neuroendocrine tumors for estimating tumor progression. Atypical carcinoids have higher Ki-67 index and have an increased propensity to metastasize as compared to typical ones.68Ga-DOTATATE PET imaging along with Ki-67 can be correlated for better management of patients with neuroendocrine tumors. We describe the dual tracer imaging features in a patient of pulmonary carcinoid with avid 68Ga-DOTATATE and minimal 18FDG (18Flurodeoxyglucose) uptake diagnosed on the basis of imaging and bronchoscopic biopsy and its correlation with tumor proliferation index.
ISSN:0972-3919
0974-0244
DOI:10.4103/0972-3919.198476