Hemodynamic effects of short-term hyperoxia after coronary artery bypass grafting

Background Although oxygen is generally administered in a liberal manner in the perioperative setting, the effects of oxygen administration on dynamic cardiovascular parameters, filling status and cerebral perfusion have not been fully unraveled. Our aim was to study the acute hemodynamic and microc...

Full description

Saved in:
Bibliographic Details
Published in:Annals of intensive care 2017-02, Vol.7 (1), p.20-20, Article 20
Main Authors: Helmerhorst, Hendrik J. F., de Wilde, Rob B. P., Lee, Dae Hyun, Palmen, Meindert, Jansen, Jos R. C., van Westerloo, David J., de Jonge, Evert
Format: Article
Language:English
Subjects:
Anesthesiology
Circulatory system
Coronary vessels
Critical Care Medicine
Emergency Medicine
Flow velocity
Heart surgery
Hemodynamics
Hyperoxia
Intensive
Intensive care
Medicine
Medicine & Public Health
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Although oxygen is generally administered in a liberal manner in the perioperative setting, the effects of oxygen administration on dynamic cardiovascular parameters, filling status and cerebral perfusion have not been fully unraveled. Our aim was to study the acute hemodynamic and microcirculatory changes before, during and after arterial hyperoxia in mechanically ventilated patients after coronary artery bypass grafting (CABG) surgery. Methods This was a single-center physiological study in a tertiary care ICU in the Netherlands. Twenty-two patients scheduled for ICU admission after elective CABG were enrolled in the study between September 2014 and September 2015. In the ICU, patients were exposed to a fraction of inspired oxygen (FiO 2 ) of 90% allowing a 15-min wash-in period. Various hemodynamic parameters were measured using direct pressure signals and continuous arterial waveform analysis at three sequential time points: before, during and after hyperoxia. Results During a 15-min exposure to a fraction of inspired oxygen (FiO 2 ) of 90%, the partial pressure of arterial oxygen (PaO 2 ) and arterial oxygen saturation (SaO 2 ) were significantly higher. The systemic resistance increased ( P  
ISSN:2110-5820
2110-5820
DOI:10.1186/s13613-017-0246-9