Comparison of direct measures of adiposity with indirect measures for assessing cardiometabolic risk factors in preadolescent girls

Childhood overweight and obesity remains high, contributing to cardiometabolic risk factors at younger ages. It is unclear which measures of adiposity serve as the best proxies for identifying children at metabolic risk. This study assessed whether DXA-derived direct measures of adiposity are more s...

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Bibliographic Details
Published in:Nutrition journal 2017-02, Vol.16 (1), p.15-15, Article 15
Main Authors: Hetherington-Rauth, Megan, Bea, Jennifer W, Lee, Vinson R, Blew, Robert M, Funk, Janet, Lohman, Timothy G, Going, Scott B
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Adiposity
Analysis
Automation
Blood Glucose - metabolism
Body Composition
Body fat
Body Mass Index
C-Reactive Protein - metabolism
Cardiovascular diseases
Cardiovascular Diseases - blood
Cardiovascular Diseases - epidemiology
Child
Childhood obesity
Children & youth
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Comparative analysis
Complications and side effects
Cross-Sectional Studies
Diabetes
Female
Glucose
Health aspects
High density lipoprotein
Humans
Insulin resistance
Linear Models
Medical laboratories
Metabolic Syndrome - blood
Metabolic Syndrome - epidemiology
Metabolism
Obesity - blood
Obesity - epidemiology
Physiological aspects
Questionnaires
Radiation
Retrospective Studies
Risk Factors
Triglycerides - blood
Type 2 diabetes
Waist Circumference
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Summary:Childhood overweight and obesity remains high, contributing to cardiometabolic risk factors at younger ages. It is unclear which measures of adiposity serve as the best proxies for identifying children at metabolic risk. This study assessed whether DXA-derived direct measures of adiposity are more strongly related to cardiometabolic risk factors in children than indirect measures. Anthropometric and DXA measures of adiposity and a comprehensive assessment of cardiometabolic risk factors were obtained in 288, 9-12 year old girls, most being of Hispanic ethnicity. Multiple regression models for each metabolic parameter were run against each adiposity measure while controlling for maturation and ethnicity. In addition, regression models including both indirect and direct measures were developed to assess whether using direct measures of adiposity could provide a better prediction of the cardiometabolic risk factors beyond that of using indirect measures alone. Measures of adiposity were significantly correlated with cardiometabolic risk factors (p 
ISSN:1475-2891
1475-2891
DOI:10.1186/s12937-017-0236-7