Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study

• Published in: Drugs -- real world outcomes 2017-03, Vol.4 (1), p.21-31
• Main Authors: Crawford, Bruce, Hashim, Siti Sabzah Mohd, Prepageran, Narayanan, See, Goh Bee, Meier, Genevieve, Wada, Keiko, Coon, Cheryl, Delgleize, Emmanuelle, DeRosa, Michael
• Format: Article
• Language: English
• Subjects: Age; Caregivers; Children & youth; Childrens health; Chronic illnesses; Costs; Ear diseases; Economic impact; Families & family life; Health care expenditures; Infections; Internal Medicine; Medicine; Medicine & Public Health; Observational studies; Original; Original Research Article; Parents & parenting; Patients; Pediatrics; Pharmacology/Toxicology; Pharmacotherapy; Population; Productivity; Quality of life; Questionnaires; Reconciliation
• ISSN: 2199-1154; 2198-9788
• DOI: 10.1007/s40801-016-0099-9

Background Acute otitis media (AOM) affects both child and parental quality of life (QoL). Data on QoL associated with AOM in Malaysia is sparse, and the burden of indirect costs have not been previously reported. Objective To determine the effect of pediatric AOM on child and parental QoL in Malaysia and its economic impact (indirect costs). Methods We utilized a set of QoL questionnaires (PAR-AOM-QOL, OM-6, and EQ-5D) combined with questions addressing work/productivity loss and financial costs associated with caring for a child during his or her illness in an observational, multicenter, prospective study. Results One hundred and ten AOM patients aged ≤5 years were included in the analysis. The majority of respondents were the patient’s mother. Parental QoL was negatively affected for both emotional and daily disturbance scales, but the level of disturbance was low. Using OM-6, the greatest negative impact was on the child’s QoL, followed by caregiver concerns, physical suffering, and emotional distress. Using EQ-5D, a moderately positive relationship between parents’ emotional disturbance and daily disturbance, and a weak, negative correlation between parental emotional disturbance and parental health status was found. Parents with paid employment took an average of 21 h from work to care for their child, at an average cost of 321.8 Malaysian ringgit (US$97) in addition to their contribution to direct medical costs. Productivity losses whilst at work, uncompensated wage losses, and leisure time losses are also reported. Conclusions This study found that AOM is associated with some negative impact on parental QoL and significant economic impact at both patient and societal levels. The findings provide useful data on healthcare resource utilization and disease burden of AOM in Malaysia.