Is chronic kidney disease an adverse factor in lung cancer clinical outcome? A propensity score matching study

Background Comorbidity has a great impact on lung cancer survival. Renal function status may affect treatment decisions and drug toxicity. The survival outcome in lung cancer patients with coexisting chronic kidney disease (CKD) has not been fully evaluated. We hypothesized that CKD is an independen...

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Bibliographic Details
Published in:Thoracic cancer 2017-03, Vol.8 (2), p.106-113
Main Authors: Lu, Ming‐Shian, Chen, Miao‐Fen, Lin, Chien‐Chao, Tseng, Yuan‐Hsi, Huang, Yao‐Kuang, Liu, Hui‐Ping, Tsai, Ying‐Huang
Format: Article
Language:English
Subjects:
Age
Aged
Aged, 80 and over
Cancer
Cancer patients
Care and treatment
Chronic illnesses
Chronic kidney disease
Chronic kidney failure
Clinical outcomes
Comorbidity
Female
Gender
Glomerular Filtration Rate
Health insurance
Histology
Hospitals
Humans
Kaplan-Meier Estimate
Kidney diseases
Lung cancer
Lung Neoplasms - mortality
Male
Medical diagnosis
Medical records
Medical treatment
Mortality
Neoplasm Staging
Oncology, Experimental
Original
outcome
Patient outcomes
Propensity Score
Renal Insufficiency, Chronic - physiopathology
Retrospective Studies
Risk Factors
survival
Survival Analysis
Tomography
Variables
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Summary:Background Comorbidity has a great impact on lung cancer survival. Renal function status may affect treatment decisions and drug toxicity. The survival outcome in lung cancer patients with coexisting chronic kidney disease (CKD) has not been fully evaluated. We hypothesized that CKD is an independent risk factor for mortality in patients with lung cancer. Methods A retrospective, propensity‐matched study of 434 patients diagnosed between June 2004 and May 2012 was conducted. CKD was defined as estimated glomerular filtration rate
ISSN:1759-7706
1759-7714
DOI:10.1111/1759-7714.12414