Is the neutrophil-to-lymphocyte ratio indicative of inflammatory state in patients with obesity and metabolic syndrome?

Obesity causes subclinical inflammation. Leukocyte count and high-sensitivity C-reactive protein (hs-CRP) are used to indicate inflammation in clinical practice. Also, inflammatory markers are evaluated as important indicators of cardiovascular risk in patients with obesity and metabolic syndrome (M...

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Bibliographic Details
Published in:Anatolian journal of cardiology 2015-10, Vol.15 (10), p.816-822
Main Authors: Bahadır, Anzel, Baltacı, Davut, Türker, Yasemin, Türker, Yasin, Iliev, Darkov, Öztürk, Serkan, Deler, Mehmet Harun, Sarıgüzel, Yunus Cem
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biomarkers - blood
Blood Cell Count
Cross-Sectional Studies
Female
Humans
Inflammation - blood
Lymphocytes - physiology
Male
Metabolic Syndrome - complications
Metabolic Syndrome - physiopathology
Middle Aged
Neutrophils - physiology
Obesity - complications
Obesity - physiopathology
Original Investigation
Young Adult
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Summary:Obesity causes subclinical inflammation. Leukocyte count and high-sensitivity C-reactive protein (hs-CRP) are used to indicate inflammation in clinical practice. Also, inflammatory markers are evaluated as important indicators of cardiovascular risk in patients with obesity and metabolic syndrome (MetS). We aimed to investigate the usage of the neutrophil-lymphocyte ratio (NLR) as an inflammatory marker in obese patients with and without MetS. The study included a total of 1267 patients. The patients were assigned groups according to degree of obesity and status of MetS. Metabolic and inflammatory markers were compared between groups, and correlation analysis was performed. Leukocyte count and hs-CRP were significantly different (p
ISSN:2149-2263
2149-2271
DOI:10.5152/akd.2014.5787