Prognostic Significance of Neutrophil to Lymphocyte Ratio, Lymphocyte to Monocyte Ratio, and Platelet to Lymphocyte Ratio in Patients with Nasopharyngeal Carcinoma

The peripheral blood neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and platelet to lymphocyte ratio (PLR) have been reported to correlate with the prognosis of many malignancies. This study evaluated the prognostic value of pretreatment NLR, LMR, and PLR in nasopharyngeal...

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Bibliographic Details
Published in:BioMed research international 2017-01, Vol.2017 (2017), p.1-6
Main Authors: Cai, Yonglin, Ou, Ningjiang, Zhong, Weiming, Wu, Huihui, Li, Jun, Tang, Minzhong, Zheng, Yuming, Li, Haifeng, Lu, Aiying, Gao, Jianquan
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Angiogenesis
Blood Platelets
Cancer
Cancer therapies
Carcinoma
Cell growth
Chemotherapy
Child
Cytokines
Disease-Free Survival
Female
Health aspects
Hematology
Humans
Laboratories
Leukocytes
Lymphocyte Count
Lymphocytes
Male
Medical prognosis
Metastasis
Middle Aged
Monocytes
Nasopharyngeal cancer
Nasopharyngeal Carcinoma
Nasopharyngeal Neoplasms - blood
Nasopharyngeal Neoplasms - mortality
Neutrophils
Patients
Physiological aspects
Platelet Count
Radiation therapy
Statistical analysis
Survival Rate
Tumor necrosis factor-TNF
Tumors
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Summary:The peripheral blood neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and platelet to lymphocyte ratio (PLR) have been reported to correlate with the prognosis of many malignancies. This study evaluated the prognostic value of pretreatment NLR, LMR, and PLR in nasopharyngeal carcinoma (NPC). A retrospective analysis of clinical and pathological data of 140 NPC patients without distant metastasis during initial treatment was conducted to identify correlations between NLR, LMR, and PLR and clinicopathological features, overall survival, and progression-free survival. Cox proportional hazard regression analysis was used to reveal the independent factors affecting the prognosis of NPC patients. NLR was associated with T staging, N staging, and overall clinical stage grouping of the NPC patients (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2017/3047802