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Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection

Globally, extra-intestinal pathogenic are one of the predominant causative agents of bacteraemia. This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was...

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Published in:JMM Case Reports (Online) 2016-10, Vol.3 (5), p.e005061
Main Authors: Mac Aogáin, Micheál, Miajlovic, Helen, Moloney, Geraldine, Chotirmall, Sanjay H, Rogers, Thomas R, Smith, Stephen G J
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Miajlovic, Helen
Moloney, Geraldine
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description Globally, extra-intestinal pathogenic are one of the predominant causative agents of bacteraemia. This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage. This is the first report of a novel ST, ST-458, which caused pyelonephritis and bacteraemia.
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title Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection
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