Serum neutrophil gelatinase-associated lipocalin has an advantage over serum cystatin C and glomerular filtration rate in prediction of adverse cardiovascular outcome in patients with ST-segment elevation myocardial infarction

The aim of this study was to assess significance of serum neutrophil gelatinase-associated lipocalin (sNGAL) and cystatin C (sCC) in prediction of adverse cardiovascular outcome after ST-segment elevation myocardial infarction (STEMI). We recruited 357 consecutive patients who were admitted to the h...

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Published in:BMC cardiovascular disorders 2017-03, Vol.17 (1), p.81-81, Article 81
Main Authors: Barbarash, Olga L, Bykova, Irina S, Kashtalap, Vasiliy V, Zykov, Mikhail V, Hryachkova, Oksana N, Kalaeva, Victoria V, Shafranskaya, Kristina S, Karetnikova, Victoria N, Kutikhin, Anton G
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Age
Angina pectoris
Atherosclerosis
Biomarkers - blood
Body mass index
Cardiology
Cardiovascular disease
Cardiovascular diseases
Collaboration
Coronary vessels
Cystatin C
Cystatin C - blood
Diabetes
Enzymes
Family medical history
Female
Follow-Up Studies
Gelatinase
Glomerular filtration rate
Glomerular Filtration Rate - physiology
Heart attacks
Heart failure
Heart surgery
Hospitals
Humans
Hypertension
Incidence
Kidneys
Lipocalin
Lipocalin-2 - blood
Male
Medical imaging
Middle Aged
Myocardial infarction
Neutrophils
Prognosis
Renal function
Renal Insufficiency - diagnosis
Renal Insufficiency - epidemiology
Renal Insufficiency - etiology
ROC Curve
Siberia - epidemiology
ST Elevation Myocardial Infarction - blood
ST Elevation Myocardial Infarction - complications
ST Elevation Myocardial Infarction - mortality
Survival Rate - trends
Task forces
Time Factors
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Summary:The aim of this study was to assess significance of serum neutrophil gelatinase-associated lipocalin (sNGAL) and cystatin C (sCC) in prediction of adverse cardiovascular outcome after ST-segment elevation myocardial infarction (STEMI). We recruited 357 consecutive patients who were admitted to the hospital within 24 h after onset of STEMI. On the 1st and 12th-14th day after hospital admission, we measured levels of sNGAL and sCC. We also determined presence of renal dysfunction (RD), defined as glomerular filtration rate 
ISSN:1471-2261
1471-2261
DOI:10.1186/s12872-017-0514-5