Ag/AgO Nanoparticles Grown via Time Dependent Double Mechanism in a 2D Layered Ni-PCP and Their Antibacterial Efficacy

• Published in: Scientific reports 2017-03, Vol.7 (1), p.44852-44852, Article 44852
• Main Authors: Agarwal, Rashmi A., Gupta, Neeraj K., Singh, Rajan, Nigam, Shivansh, Ateeq, Bushra
• Format: Article
• Language: English
• Subjects: 14/3; 140/146; 639/638/45/957; 639/638/92/314; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Cytotoxicity; E coli; Escherichia coli - drug effects; Humanities and Social Sciences; Metal Nanoparticles - chemistry; Metal Nanoparticles - ultrastructure; Metal-Organic Frameworks - chemistry; Metal-Organic Frameworks - pharmacology; Metal-Organic Frameworks - ultrastructure; Microbial Sensitivity Tests; Microscopy, Atomic Force; Models, Molecular; Molecular Conformation; multidisciplinary; Nanoparticles; Nickel - chemistry; Nodes; Oxides - chemistry; Oxides - pharmacology; Particle Size; Polymers; Science; Silver - chemistry; Silver - pharmacology; Silver Compounds - chemistry; Silver Compounds - pharmacology; Size distribution; X-Ray Diffraction
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/srep44852

A simple synthesis route for growth of Ag/AgO nanoparticles (NPs) in large quantitative yields with narrow size distribution from a functional, non-activated, Ni (II) based highly flexible porous coordination polymer (PCP) as a template has been demonstrated. This template is a stable storage media for the NPs larger than the pore diameters of the PCP. From EPR study it was concluded that NPs were synthesized via two mechanisms i.e. acid formation and the redox activity of the framework. Size range of Ag/AgO NPs is sensitive to choice of solvent and reaction time. Direct use of Ag/AgO@Ni-PCP shows influential growth inhibition towards Escherichia coli and the pathogen Salmonella typhimurium at extremely low concentrations. The pristine template shows no cytotoxic activity, even though it contains Ni nodes in the framework.