Determinants to antiretroviral treatment non-adherence among adult HIV/AIDS patients in northern Ethiopia

Adhering 95% and above of antiretroviral therapy reduces the rate of disease progression and death among people's living human immunodeficiency virus. Though manifold factors have reported as determinant factors of antiretroviral therapy adherence status, perhaps determinants of non-adherence d...

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Bibliographic Details
Published in:AIDS research and therapy 2017-03, Vol.14 (1), p.16-16, Article 16
Main Authors: Gebrezgabher, Berhe Beyene, Kebede, Yigzaw, Kindie, Melaku, Tetemke, Desalegn, Abay, Mebrahtu, Gelaw, Yalemzewod Assefa
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adolescent
Adult
Adults
Aged
Aged, 80 and over
AIDS
AIDS/HIV
Anti-HIV Agents - therapeutic use
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Case-Control Studies
Data collection
Developing countries
Disease spread
Drug resistance
Drug therapy
Ethiopia
Female
Follow-Up Studies
Food
Food supply
HIV
HIV Infections - drug therapy
Hospitals
Human immunodeficiency virus
Humans
LDCs
Male
Medication Adherence
Middle Aged
Mortality
Multivariate analysis
Nutrition
Patient compliance
Patients
Public health
Questionnaires
Regression analysis
Sociodemographics
Substance use
Therapy
Viruses
Young Adult
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Summary:Adhering 95% and above of antiretroviral therapy reduces the rate of disease progression and death among people's living human immunodeficiency virus. Though manifold factors have reported as determinant factors of antiretroviral therapy adherence status, perhaps determinants of non-adherence differ up on the activities of patients in the study setting. An institution based unmatched case-control study was conducted in Aksum town. Individuals who had a 6-month follow-up with complete individual information were included in the study. Document review and interviewer based techniques were used to collect the data. Binary logistic regression analysis was used to identify the determinant factors of non-adherence. A total of 411 (137 cases and 274 control) study participants were included in the study. The majority of them were male in sex. Having 2 years and above duration on ART [AOR = 7, 95% CI (2.2, 22.6)], history of adverse effect [AOR = 6.9, 95% CI (1.4, 32.9)], substance use [AOR = 5.3, 95% CI (1.4, 20.0)], living with parents [AOR = 3.4, 95% CI (1.2, 10.3)], having depression symptom [AOR = 3.3, 95% CI (1.4, 7.5)], 
ISSN:1742-6405
1742-6405
DOI:10.1186/s12981-017-0143-1