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Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries
Abstract Background Activity limitation stages based on activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are associated with 3-year mortality in elderly Medicare beneficiaries, yet their associations with hospitalization risk in this population have not been stud...
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Published in: | PM & R 2016-09, Vol.9 (5), p.433-443 |
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creator | Na, Ling, PhD Pan, Qiang, MA Xie, Dawei, PhD Kurichi, Jibby E., MPH Streim, Joel E., MD Bogner, Hillary R., MD, MSCE Saliba, Debra, MD, MPH, AGSF Hennessy, Sean, PharmD, PhD |
description | Abstract Background Activity limitation stages based on activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are associated with 3-year mortality in elderly Medicare beneficiaries, yet their associations with hospitalization risk in this population have not been studied. Objective To examine the independent association of activity limitation stages with risk of hospitalization within a year among Medicare beneficiaries aged 65 years and older. Design Cohort study. Setting Community. Participants A total of 9447 community-dwelling elderly Medicare beneficiaries from the Medicare Current Beneficiary Survey (MCBS) for years 2005-2009. Methods Stages were derived for ADLs and IADLs separately. Associations of stages with time to first hospitalization and time to recurrent hospitalizations within a year were assessed with Cox proportional hazards models, accounting for baseline sociodemographics, smoking status, comorbidities, and the year of survey entry. Main Outcomes Time to first hospitalization and time to recurrent hospitalizations within one year. Principle Findings The adjusted risk of first hospitalization increased with higher activity limitation stages (except stage III). The hazard ratios (95% confidence intervals) for ADL stages I-IV compared to stage 0 (no limitations) were 1.49 (1.36-1.63), 1.61 (1.44-1.80), 1.54 (1.35-1.76), and 2.06 (1.61-2.63), respectively. The pattern for IADL stages was similar. For recurrent hospitalizations, activity limitation stages were associated with the risk of the first hospitalization, but not with subsequent hospitalizations. Conclusion Activity limitation stages are associated with the risk of first hospitalization in the subsequent year among elderly Medicare beneficiaries. Stages capture clinically interpretable profiles of ADL and IADL functionality and describe preserved functions and activity limitation in an aggregated measure. Stage can inform interventions to ameliorate disability, and thus reduce the risk of a subsequent hospitalization in this population. |
doi_str_mv | 10.1016/j.pmrj.2016.09.008 |
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fullrecord | <record><control><sourceid>elsevier_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5360539</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1934148216309662</els_id><sourcerecordid>1_s2_0_S1934148216309662</sourcerecordid><originalsourceid>FETCH-LOGICAL-e1109-d521a071933ee51e68421c026f9327f100c86b75a2a24813d0b8f4f748f4555a3</originalsourceid><addsrcrecordid>eNpVUNtKw0AQXUTx_gM-5QcaZ69JXoQqaoWKYPV53SaTdtpcSjat1K93SxXxZebAnHM4cxi74hBz4OZ6Ea_qbhGLgGPIYoD0gJ3yTKoB10Ye_mKVihN25v0CwCiemmN2IhJjlAJ9yj6GeU8b6rfRmGrqXU9tE016N0MfDTuMht63Obkei-iT-nk0av0q0Cr62lNfyS8jV7fNLHrGgnIXNLfYYElB1RH6C3ZUusrj5c8-Z-8P9293o8H45fHpbjgeIOeQDQotuIMkJJaImqNJleA5CFNmUiQlB8hTM020E06olMsCpmmpykSFqbV28pzd7H1X62mNRY5N37nKrjqqXbe1rSP7_9LQ3M7ajdXSgJbZnwGGlBvCzuYVNeGjaolb9It23TXhAcutFxbsZFfurltuJGTGCPkNzLJ5Nw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Na, Ling, PhD ; Pan, Qiang, MA ; Xie, Dawei, PhD ; Kurichi, Jibby E., MPH ; Streim, Joel E., MD ; Bogner, Hillary R., MD, MSCE ; Saliba, Debra, MD, MPH, AGSF ; Hennessy, Sean, PharmD, PhD</creator><creatorcontrib>Na, Ling, PhD ; Pan, Qiang, MA ; Xie, Dawei, PhD ; Kurichi, Jibby E., MPH ; Streim, Joel E., MD ; Bogner, Hillary R., MD, MSCE ; Saliba, Debra, MD, MPH, AGSF ; Hennessy, Sean, PharmD, PhD</creatorcontrib><description>Abstract Background Activity limitation stages based on activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are associated with 3-year mortality in elderly Medicare beneficiaries, yet their associations with hospitalization risk in this population have not been studied. Objective To examine the independent association of activity limitation stages with risk of hospitalization within a year among Medicare beneficiaries aged 65 years and older. Design Cohort study. Setting Community. Participants A total of 9447 community-dwelling elderly Medicare beneficiaries from the Medicare Current Beneficiary Survey (MCBS) for years 2005-2009. Methods Stages were derived for ADLs and IADLs separately. Associations of stages with time to first hospitalization and time to recurrent hospitalizations within a year were assessed with Cox proportional hazards models, accounting for baseline sociodemographics, smoking status, comorbidities, and the year of survey entry. Main Outcomes Time to first hospitalization and time to recurrent hospitalizations within one year. Principle Findings The adjusted risk of first hospitalization increased with higher activity limitation stages (except stage III). The hazard ratios (95% confidence intervals) for ADL stages I-IV compared to stage 0 (no limitations) were 1.49 (1.36-1.63), 1.61 (1.44-1.80), 1.54 (1.35-1.76), and 2.06 (1.61-2.63), respectively. The pattern for IADL stages was similar. For recurrent hospitalizations, activity limitation stages were associated with the risk of the first hospitalization, but not with subsequent hospitalizations. Conclusion Activity limitation stages are associated with the risk of first hospitalization in the subsequent year among elderly Medicare beneficiaries. Stages capture clinically interpretable profiles of ADL and IADL functionality and describe preserved functions and activity limitation in an aggregated measure. Stage can inform interventions to ameliorate disability, and thus reduce the risk of a subsequent hospitalization in this population.</description><identifier>ISSN: 1934-1482</identifier><identifier>EISSN: 1934-1563</identifier><identifier>DOI: 10.1016/j.pmrj.2016.09.008</identifier><identifier>PMID: 27664405</identifier><language>eng</language><subject>Physical Medicine and Rehabilitation</subject><ispartof>PM & R, 2016-09, Vol.9 (5), p.433-443</ispartof><rights>American Academy of Physical Medicine and Rehabilitation</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids></links><search><creatorcontrib>Na, Ling, PhD</creatorcontrib><creatorcontrib>Pan, Qiang, MA</creatorcontrib><creatorcontrib>Xie, Dawei, PhD</creatorcontrib><creatorcontrib>Kurichi, Jibby E., MPH</creatorcontrib><creatorcontrib>Streim, Joel E., MD</creatorcontrib><creatorcontrib>Bogner, Hillary R., MD, MSCE</creatorcontrib><creatorcontrib>Saliba, Debra, MD, MPH, AGSF</creatorcontrib><creatorcontrib>Hennessy, Sean, PharmD, PhD</creatorcontrib><title>Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries</title><title>PM & R</title><description>Abstract Background Activity limitation stages based on activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are associated with 3-year mortality in elderly Medicare beneficiaries, yet their associations with hospitalization risk in this population have not been studied. Objective To examine the independent association of activity limitation stages with risk of hospitalization within a year among Medicare beneficiaries aged 65 years and older. Design Cohort study. Setting Community. Participants A total of 9447 community-dwelling elderly Medicare beneficiaries from the Medicare Current Beneficiary Survey (MCBS) for years 2005-2009. Methods Stages were derived for ADLs and IADLs separately. Associations of stages with time to first hospitalization and time to recurrent hospitalizations within a year were assessed with Cox proportional hazards models, accounting for baseline sociodemographics, smoking status, comorbidities, and the year of survey entry. Main Outcomes Time to first hospitalization and time to recurrent hospitalizations within one year. Principle Findings The adjusted risk of first hospitalization increased with higher activity limitation stages (except stage III). The hazard ratios (95% confidence intervals) for ADL stages I-IV compared to stage 0 (no limitations) were 1.49 (1.36-1.63), 1.61 (1.44-1.80), 1.54 (1.35-1.76), and 2.06 (1.61-2.63), respectively. The pattern for IADL stages was similar. For recurrent hospitalizations, activity limitation stages were associated with the risk of the first hospitalization, but not with subsequent hospitalizations. Conclusion Activity limitation stages are associated with the risk of first hospitalization in the subsequent year among elderly Medicare beneficiaries. Stages capture clinically interpretable profiles of ADL and IADL functionality and describe preserved functions and activity limitation in an aggregated measure. Stage can inform interventions to ameliorate disability, and thus reduce the risk of a subsequent hospitalization in this population.</description><subject>Physical Medicine and Rehabilitation</subject><issn>1934-1482</issn><issn>1934-1563</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpVUNtKw0AQXUTx_gM-5QcaZ69JXoQqaoWKYPV53SaTdtpcSjat1K93SxXxZebAnHM4cxi74hBz4OZ6Ea_qbhGLgGPIYoD0gJ3yTKoB10Ye_mKVihN25v0CwCiemmN2IhJjlAJ9yj6GeU8b6rfRmGrqXU9tE016N0MfDTuMht63Obkei-iT-nk0av0q0Cr62lNfyS8jV7fNLHrGgnIXNLfYYElB1RH6C3ZUusrj5c8-Z-8P9293o8H45fHpbjgeIOeQDQotuIMkJJaImqNJleA5CFNmUiQlB8hTM020E06olMsCpmmpykSFqbV28pzd7H1X62mNRY5N37nKrjqqXbe1rSP7_9LQ3M7ajdXSgJbZnwGGlBvCzuYVNeGjaolb9It23TXhAcutFxbsZFfurltuJGTGCPkNzLJ5Nw</recordid><startdate>20160921</startdate><enddate>20160921</enddate><creator>Na, Ling, PhD</creator><creator>Pan, Qiang, MA</creator><creator>Xie, Dawei, PhD</creator><creator>Kurichi, Jibby E., MPH</creator><creator>Streim, Joel E., MD</creator><creator>Bogner, Hillary R., MD, MSCE</creator><creator>Saliba, Debra, MD, MPH, AGSF</creator><creator>Hennessy, Sean, PharmD, PhD</creator><scope>5PM</scope></search><sort><creationdate>20160921</creationdate><title>Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries</title><author>Na, Ling, PhD ; Pan, Qiang, MA ; Xie, Dawei, PhD ; Kurichi, Jibby E., MPH ; Streim, Joel E., MD ; Bogner, Hillary R., MD, MSCE ; Saliba, Debra, MD, MPH, AGSF ; Hennessy, Sean, PharmD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e1109-d521a071933ee51e68421c026f9327f100c86b75a2a24813d0b8f4f748f4555a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Physical Medicine and Rehabilitation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Na, Ling, PhD</creatorcontrib><creatorcontrib>Pan, Qiang, MA</creatorcontrib><creatorcontrib>Xie, Dawei, PhD</creatorcontrib><creatorcontrib>Kurichi, Jibby E., MPH</creatorcontrib><creatorcontrib>Streim, Joel E., MD</creatorcontrib><creatorcontrib>Bogner, Hillary R., MD, MSCE</creatorcontrib><creatorcontrib>Saliba, Debra, MD, MPH, AGSF</creatorcontrib><creatorcontrib>Hennessy, Sean, PharmD, PhD</creatorcontrib><collection>PubMed Central (Full Participant titles)</collection><jtitle>PM & R</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Na, Ling, PhD</au><au>Pan, Qiang, MA</au><au>Xie, Dawei, PhD</au><au>Kurichi, Jibby E., MPH</au><au>Streim, Joel E., MD</au><au>Bogner, Hillary R., MD, MSCE</au><au>Saliba, Debra, MD, MPH, AGSF</au><au>Hennessy, Sean, PharmD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries</atitle><jtitle>PM & R</jtitle><date>2016-09-21</date><risdate>2016</risdate><volume>9</volume><issue>5</issue><spage>433</spage><epage>443</epage><pages>433-443</pages><issn>1934-1482</issn><eissn>1934-1563</eissn><abstract>Abstract Background Activity limitation stages based on activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are associated with 3-year mortality in elderly Medicare beneficiaries, yet their associations with hospitalization risk in this population have not been studied. Objective To examine the independent association of activity limitation stages with risk of hospitalization within a year among Medicare beneficiaries aged 65 years and older. Design Cohort study. Setting Community. Participants A total of 9447 community-dwelling elderly Medicare beneficiaries from the Medicare Current Beneficiary Survey (MCBS) for years 2005-2009. Methods Stages were derived for ADLs and IADLs separately. Associations of stages with time to first hospitalization and time to recurrent hospitalizations within a year were assessed with Cox proportional hazards models, accounting for baseline sociodemographics, smoking status, comorbidities, and the year of survey entry. Main Outcomes Time to first hospitalization and time to recurrent hospitalizations within one year. Principle Findings The adjusted risk of first hospitalization increased with higher activity limitation stages (except stage III). The hazard ratios (95% confidence intervals) for ADL stages I-IV compared to stage 0 (no limitations) were 1.49 (1.36-1.63), 1.61 (1.44-1.80), 1.54 (1.35-1.76), and 2.06 (1.61-2.63), respectively. The pattern for IADL stages was similar. For recurrent hospitalizations, activity limitation stages were associated with the risk of the first hospitalization, but not with subsequent hospitalizations. Conclusion Activity limitation stages are associated with the risk of first hospitalization in the subsequent year among elderly Medicare beneficiaries. Stages capture clinically interpretable profiles of ADL and IADL functionality and describe preserved functions and activity limitation in an aggregated measure. Stage can inform interventions to ameliorate disability, and thus reduce the risk of a subsequent hospitalization in this population.</abstract><pmid>27664405</pmid><doi>10.1016/j.pmrj.2016.09.008</doi><tpages>11</tpages></addata></record> |
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title | Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries |
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