Loose Anchoring of Anagen Hairs and Pili Torti due to Erlotinib

Erlotinib is a selective epidermal growth factor receptor inhibitor utilized in the treatment of solid tumors. Cutaneous side effects, including changes in hair texture and alopecia, have been described. In this case report, we describe two patients with a new finding of loose anagen hairs and pili...

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Bibliographic Details
Published in:International journal of trichology 2016-10, Vol.8 (4), p.186-187
Main Authors: Pirmez, Rodrigo, Piñeiro-Maceira, Juan, Gonzalez, Carmen Gloria, Miteva, Mariya
Format: Article
Language:English
Subjects:
Alopecia
Biopsy
Case Report
Case studies
Complications and side effects
Corticosteroid drugs
Diagnosis
Dosage and administration
Drug therapy
Epidermal growth factor
Erlotinib
Growth factors
Hair loss
Minoxidil
Patients
Risk factors
Side effects
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Summary:Erlotinib is a selective epidermal growth factor receptor inhibitor utilized in the treatment of solid tumors. Cutaneous side effects, including changes in hair texture and alopecia, have been described. In this case report, we describe two patients with a new finding of loose anagen hairs and pili torti leading to nonscarring marginal and diffuse alopecia and discuss potential mechanisms underlying erlotinib-induced hair changes.
ISSN:0974-7753
0974-9241
DOI:10.4103/ijt.ijt_16_16