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REM theta activity enhances inhibitory control in typically developing children but not children with ADHD symptoms
Sleep disturbances impair cognitive functioning in typically developing populations. Children with attention-deficit/hyperactivity disorder (ADHD), a disorder characterized by impaired inhibitory control and attention, commonly experience sleep disturbances. Whether inhibitory impairments are relate...
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| Published in: | Experimental brain research 2017-05, Vol.235 (5), p.1491-1500 |
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| cites | cdi_FETCH-LOGICAL-c635t-793a8b81cf221252ddb4110177535a8c674eee22f8c078d5180c81c7ae96cc3a3 |
| container_end_page | 1500 |
| container_issue | 5 |
| container_start_page | 1491 |
| container_title | Experimental brain research |
| container_volume | 235 |
| creator | Cremone, Amanda Lugo-Candelas, Claudia I. Harvey, Elizabeth A. McDermott, Jennifer M. Spencer, Rebecca M. C. |
| description | Sleep disturbances impair cognitive functioning in typically developing populations. Children with attention-deficit/hyperactivity disorder (ADHD), a disorder characterized by impaired inhibitory control and attention, commonly experience sleep disturbances. Whether inhibitory impairments are related to sleep deficits in children with ADHD is unknown. Children with ADHD (
n
= 18;
M
age
= 6.70 years) and typically developing controls (
n
= 15;
M
age
= 6.73 years) completed a Go/No-Go task to measure inhibitory control and sustained attention before and after polysomnography-monitored overnight sleep. Inhibitory control and sustained attention were improved following overnight sleep in typically developing children. Moreover, morning inhibitory control was positively correlated with rapid eye movement (REM) theta activity in this group. Although REM theta activity was greater in children with ADHD compared to typically developing children, it was functionally insignificant. Neither inhibitory control nor sustained attention was improved following overnight sleep in children with ADHD symptoms, and neither of these behaviors was associated with REM theta activity in this group. Taken together, these results indicate that elevated REM theta activity may be functionally related to ADHD symptomology, possibly reflecting delayed cortical maturation. |
| doi_str_mv | 10.1007/s00221-017-4906-7 |
| format | article |
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n
= 18;
M
age
= 6.70 years) and typically developing controls (
n
= 15;
M
age
= 6.73 years) completed a Go/No-Go task to measure inhibitory control and sustained attention before and after polysomnography-monitored overnight sleep. Inhibitory control and sustained attention were improved following overnight sleep in typically developing children. Moreover, morning inhibitory control was positively correlated with rapid eye movement (REM) theta activity in this group. Although REM theta activity was greater in children with ADHD compared to typically developing children, it was functionally insignificant. Neither inhibitory control nor sustained attention was improved following overnight sleep in children with ADHD symptoms, and neither of these behaviors was associated with REM theta activity in this group. Taken together, these results indicate that elevated REM theta activity may be functionally related to ADHD symptomology, possibly reflecting delayed cortical maturation.</description><identifier>ISSN: 0014-4819</identifier><identifier>EISSN: 1432-1106</identifier><identifier>DOI: 10.1007/s00221-017-4906-7</identifier><identifier>PMID: 28246970</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Attention Deficit Disorder with Hyperactivity - complications ; Attention deficit hyperactivity disorder ; Biomedical and Life Sciences ; Biomedicine ; Brain Mapping ; Child ; Child Development - physiology ; Child, Preschool ; Complications and side effects ; Eye movements ; Female ; Humans ; Hyperactivity ; Hypotheses ; Inhibition (Psychology) ; Male ; Neurology ; Neuropsychological Tests ; Neurosciences ; Physiological aspects ; Polysomnography ; Psychiatric Status Rating Scales ; Psychological aspects ; Rapid eye movement ; Research Article ; Risk factors ; Sleep ; Sleep deprivation ; Sleep Wake Disorders - etiology ; Sleep, REM - physiology ; Theta Rhythm - physiology ; Young adults</subject><ispartof>Experimental brain research, 2017-05, Vol.235 (5), p.1491-1500</ispartof><rights>Springer-Verlag Berlin Heidelberg 2017</rights><rights>COPYRIGHT 2017 Springer</rights><rights>Experimental Brain Research is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c635t-793a8b81cf221252ddb4110177535a8c674eee22f8c078d5180c81c7ae96cc3a3</citedby><cites>FETCH-LOGICAL-c635t-793a8b81cf221252ddb4110177535a8c674eee22f8c078d5180c81c7ae96cc3a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1883972269/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1883972269?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,780,784,885,21394,27924,27925,33611,33612,43733,74221</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28246970$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cremone, Amanda</creatorcontrib><creatorcontrib>Lugo-Candelas, Claudia I.</creatorcontrib><creatorcontrib>Harvey, Elizabeth A.</creatorcontrib><creatorcontrib>McDermott, Jennifer M.</creatorcontrib><creatorcontrib>Spencer, Rebecca M. C.</creatorcontrib><title>REM theta activity enhances inhibitory control in typically developing children but not children with ADHD symptoms</title><title>Experimental brain research</title><addtitle>Exp Brain Res</addtitle><addtitle>Exp Brain Res</addtitle><description>Sleep disturbances impair cognitive functioning in typically developing populations. Children with attention-deficit/hyperactivity disorder (ADHD), a disorder characterized by impaired inhibitory control and attention, commonly experience sleep disturbances. Whether inhibitory impairments are related to sleep deficits in children with ADHD is unknown. Children with ADHD (
n
= 18;
M
age
= 6.70 years) and typically developing controls (
n
= 15;
M
age
= 6.73 years) completed a Go/No-Go task to measure inhibitory control and sustained attention before and after polysomnography-monitored overnight sleep. Inhibitory control and sustained attention were improved following overnight sleep in typically developing children. Moreover, morning inhibitory control was positively correlated with rapid eye movement (REM) theta activity in this group. Although REM theta activity was greater in children with ADHD compared to typically developing children, it was functionally insignificant. Neither inhibitory control nor sustained attention was improved following overnight sleep in children with ADHD symptoms, and neither of these behaviors was associated with REM theta activity in this group. Taken together, these results indicate that elevated REM theta activity may be functionally related to ADHD symptomology, possibly reflecting delayed cortical maturation.</description><subject>Attention Deficit Disorder with Hyperactivity - complications</subject><subject>Attention deficit hyperactivity disorder</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Brain Mapping</subject><subject>Child</subject><subject>Child Development - physiology</subject><subject>Child, Preschool</subject><subject>Complications and side effects</subject><subject>Eye movements</subject><subject>Female</subject><subject>Humans</subject><subject>Hyperactivity</subject><subject>Hypotheses</subject><subject>Inhibition (Psychology)</subject><subject>Male</subject><subject>Neurology</subject><subject>Neuropsychological Tests</subject><subject>Neurosciences</subject><subject>Physiological aspects</subject><subject>Polysomnography</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychological aspects</subject><subject>Rapid eye movement</subject><subject>Research Article</subject><subject>Risk factors</subject><subject>Sleep</subject><subject>Sleep deprivation</subject><subject>Sleep Wake Disorders - etiology</subject><subject>Sleep, REM - physiology</subject><subject>Theta Rhythm - physiology</subject><subject>Young adults</subject><issn>0014-4819</issn><issn>1432-1106</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>ALSLI</sourceid><sourceid>M2R</sourceid><recordid>eNqNkt9rFDEQxxdRbK3-Ab5IQBB92Jofu5vkRTjaagsVoepzyGVnb1OyybnJnu5_b46r9U4UJA8hM5_5kpnvFMVzgk8JxvxtxJhSUmLCy0ripuQPimNSMVoSgpuHxTHGpCorQeRR8STG2-2Tcfy4OKKCVo3k-LiINxcfUeohaaRNshubZgS-195ARNb3dmlTGGdkgk9jcDmE0ry2Rjs3oxY24MLa-hUyvXXtCB4tp4R8SL8D323q0eL88hzFeVinMMSnxaNOuwjP7u6T4uv7iy9nl-X1pw9XZ4vr0jSsTiWXTIulIKbLTdKatu2yyo0RzmtWa2EaXgEApZ0wmIu2JgKbTHMNsjGGaXZSvNvprqflAK2B3IJ2aj3aQY-zCtqqw4y3vVqFjaqZZJjjLPD6TmAM3yaISQ02GnBOewhTVERIIrhoMPkPlDMm60bKjL78A70N0-jzJDIlmOSUNnvUSjtQ1nchf9FsRdWirrGsCa9Fpk7_QuXTwmCzZ9DZHD8oeHNQsPUVfqSVnmJUV59vDtlXe2wP2qU-BjclG3w8BMkONGOIcYTufsYEq-2mqt2mqmye2m6q4rnmxb459xW_VjMDdAfEnPIrGPfG9E_VnyxC8Xo</recordid><startdate>20170501</startdate><enddate>20170501</enddate><creator>Cremone, Amanda</creator><creator>Lugo-Candelas, Claudia I.</creator><creator>Harvey, Elizabeth A.</creator><creator>McDermott, Jennifer M.</creator><creator>Spencer, Rebecca M. C.</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>0-V</scope><scope>3V.</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88J</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2R</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170501</creationdate><title>REM theta activity enhances inhibitory control in typically developing children but not children with ADHD symptoms</title><author>Cremone, Amanda ; Lugo-Candelas, Claudia I. ; Harvey, Elizabeth A. ; McDermott, Jennifer M. ; Spencer, Rebecca M. 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C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>REM theta activity enhances inhibitory control in typically developing children but not children with ADHD symptoms</atitle><jtitle>Experimental brain research</jtitle><stitle>Exp Brain Res</stitle><addtitle>Exp Brain Res</addtitle><date>2017-05-01</date><risdate>2017</risdate><volume>235</volume><issue>5</issue><spage>1491</spage><epage>1500</epage><pages>1491-1500</pages><issn>0014-4819</issn><eissn>1432-1106</eissn><abstract>Sleep disturbances impair cognitive functioning in typically developing populations. Children with attention-deficit/hyperactivity disorder (ADHD), a disorder characterized by impaired inhibitory control and attention, commonly experience sleep disturbances. Whether inhibitory impairments are related to sleep deficits in children with ADHD is unknown. Children with ADHD (
n
= 18;
M
age
= 6.70 years) and typically developing controls (
n
= 15;
M
age
= 6.73 years) completed a Go/No-Go task to measure inhibitory control and sustained attention before and after polysomnography-monitored overnight sleep. Inhibitory control and sustained attention were improved following overnight sleep in typically developing children. Moreover, morning inhibitory control was positively correlated with rapid eye movement (REM) theta activity in this group. Although REM theta activity was greater in children with ADHD compared to typically developing children, it was functionally insignificant. Neither inhibitory control nor sustained attention was improved following overnight sleep in children with ADHD symptoms, and neither of these behaviors was associated with REM theta activity in this group. Taken together, these results indicate that elevated REM theta activity may be functionally related to ADHD symptomology, possibly reflecting delayed cortical maturation.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>28246970</pmid><doi>10.1007/s00221-017-4906-7</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Attention Deficit Disorder with Hyperactivity - complications Attention deficit hyperactivity disorder Biomedical and Life Sciences Biomedicine Brain Mapping Child Child Development - physiology Child, Preschool Complications and side effects Eye movements Female Humans Hyperactivity Hypotheses Inhibition (Psychology) Male Neurology Neuropsychological Tests Neurosciences Physiological aspects Polysomnography Psychiatric Status Rating Scales Psychological aspects Rapid eye movement Research Article Risk factors Sleep Sleep deprivation Sleep Wake Disorders - etiology Sleep, REM - physiology Theta Rhythm - physiology Young adults |
| title | REM theta activity enhances inhibitory control in typically developing children but not children with ADHD symptoms |
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