Diagnostic REM sleep muscle activity thresholds in idiopathic REM sleep behavior disorder patients with and without obstructive sleep apnea

Highlights • We determined visual and automated REM sleep without atonia (RSWA) diagnostic cut-offs for idiopathic REM sleep behavior disorder (iRBD) patients with comorbid obstructive sleep apnea (OSA) during split-night polysomnography. • Combining analysis of phasic muscle activity burst duration...

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Bibliographic Details
Published in:Sleep medicine 2016-05, Vol.33, p.23-29
Main Authors: McCarter, Stuart J., BA, St. Louis, Erik K., MD, Sandness, David J., BA, Duwell, Ethan J., BA, Timm, Paul C., BA, Boeve, Bradley F., MD, Silber, Michael H., MB, ChB
Format: Article
Language:English
Subjects:
Neurology
Sleep Medicine
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Summary:Highlights • We determined visual and automated REM sleep without atonia (RSWA) diagnostic cut-offs for idiopathic REM sleep behavior disorder (iRBD) patients with comorbid obstructive sleep apnea (OSA) during split-night polysomnography. • Combining analysis of phasic muscle activity burst durations with standard visual and automated methods improved sensitivity and specificity for iRBD diagnosis. • iRBD RSWA cutoffs were similar to those previously determined for PD-RBD, possibly indicating a similar underlying neurodegenerative process. • Our diagnostic RSWA cutoff values provide useful data to help physicians more accurately diagnose RBD in a clinical sleep medicine practice utilizing split-night polysomnography and conventional submentalis and anterior tibialis EMG lead placements.
ISSN:1389-9457
1878-5506
DOI:10.1016/j.sleep.2016.03.013