THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION

• Published in: African journal of traditional, complementary, and alternative medicines complementary, and alternative medicines, 2016-01, Vol.13 (5), p.190-194
• Main Authors: Zhang, Yin, dan Li, Shao, Zhang, Jun Xiu, Liu, Yi, Cui, Yi xin, Yang, Min hui
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; bronchial hyper-responsiveness; Bronchial Hyperreactivity - blood; Bronchial Hyperreactivity - drug therapy; Bronchial Hyperreactivity - physiopathology; Bronchial Provocation Tests; cough; Cough - blood; Cough - drug therapy; Cough - physiopathology; Drugs, Chinese Herbal - therapeutic use; Female; Humans; Interferon-gamma - blood; Interleukin-4 - blood; Male; Medicine, Chinese Traditional - methods; Middle Aged; Phytotherapy - methods; therapeutic mechanism; Treatment Outcome; Young Adult; Ziyinqingre prescription
• ISSN: 0189-6016; 2505-0044
• DOI: 10.21010/ajtcam.v13i5.25

Objective: Discussing the effects of Ziyinqingre prescription on the level of airway resistance (Rrs), airway response threshold (Dmin), airway conductance (sGrs) and the level of inflammatory cytokines interleukin-4 (IL-4) and interferon-γ (IFN-γ) of the bronchial hyper-responsiveness (BHR) cough patients. Method: 84 subjects diagnosed as BHR were randomly divided into 42 Chinese Traditional medicine group and 42 control group. The Chinese Traditional Medicine group received Ziyinqingre prescription twice a day and the control group received 10mg Montelukast Sodium tablets once a day for two weeks. Observe the clinical symptoms improvement and the changes of the level of the Rrs, Dmin, sGrs and IL-4, IFN-γ. Results: After receiving the medicine, the symptoms of the Chinese medicine group were obviously alleviated, the outcome was more satisfied than that of the control group. Compared with the control group, the level of Dmin increased and sGrs level decreased more obviously (P