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THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION
Objective: Discussing the effects of Ziyinqingre prescription on the level of airway resistance (Rrs), airway response threshold (Dmin), airway conductance (sGrs) and the level of inflammatory cytokines interleukin-4 (IL-4) and interferon-γ (IFN-γ) of the bronchial hyper-responsiveness (BHR) cough p...
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| Published in: | African journal of traditional, complementary, and alternative medicines complementary, and alternative medicines, 2016-01, Vol.13 (5), p.190-194 |
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| container_end_page | 194 |
| container_issue | 5 |
| container_start_page | 190 |
| container_title | African journal of traditional, complementary, and alternative medicines |
| container_volume | 13 |
| creator | Zhang, Yin dan Li, Shao Zhang, Jun Xiu Liu, Yi Cui, Yi xin Yang, Min hui |
| description | Objective: Discussing the effects of Ziyinqingre prescription on the
level of airway resistance (Rrs), airway response threshold (Dmin),
airway conductance (sGrs) and the level of inflammatory cytokines
interleukin-4 (IL-4) and interferon-γ (IFN-γ) of the
bronchial hyper-responsiveness (BHR) cough patients. Method: 84
subjects diagnosed as BHR were randomly divided into 42 Chinese
Traditional medicine group and 42 control group. The Chinese
Traditional Medicine group received Ziyinqingre prescription twice a
day and the control group received 10mg Montelukast Sodium tablets once
a day for two weeks. Observe the clinical symptoms improvement and the
changes of the level of the Rrs, Dmin, sGrs and IL-4, IFN-γ.
Results: After receiving the medicine, the symptoms of the Chinese
medicine group were obviously alleviated, the outcome was more
satisfied than that of the control group. Compared with the control
group, the level of Dmin increased and sGrs level decreased more
obviously (P |
| doi_str_mv | 10.21010/ajtcam.v13i5.25 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5416640</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1899107659</sourcerecordid><originalsourceid>FETCH-LOGICAL-b458t-9f4914cb781f0d56e466781de9488536b6dd41d7b852aa45afffde7108e6bac23</originalsourceid><addsrcrecordid>eNpVkcFvmzAUxq1p05q2u-80-bgLmQ22MZdJlLnBUgoMSKXsYhkwGxUJHZBK_e_rNW20Srb89N7v-2z5A-AzRksXI4y-6bu51rvlA_Y6unTpO7BwKaIOQoS8BwuEeeAwhNkZOJ-mO4Q8jl3_IzhzOeF-gPECHMpYQLvzMBObUkZQ3IbrTVjKNIFh8gPeiCgOE1ncQNsoc2EnyQpe5WkSxTJcw3ibidzJRZGlSSFvRSKKAkbpZhXDqy38Jbcy-WkVuYCZhaJcZv-sL8GHVveT-fRyXoDNtSij2FmnKxmFa6cilM9O0JIAk7ryOW5RQ5khjNm6MQHhnHqsYk1DcONXnLpaE6rbtm2MjxE3rNK1612A70ff-0O1M01t9vOoe3U_djs9PqpBd-rtZN_9Ub-HB0UJZowga_D1xWAc_h7MNKtdN9Wm7_XeDIdJ2Q8OMPIZDSyKjmg9DtM0mvZ0DUbqOS11TEs9p6VcaiVf_n_eSfAajwWWR6Dqhr7bmxNRj51Wr825tgsz7LneE0Ism9U</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1899107659</pqid></control><display><type>article</type><title>THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION</title><source>PubMed Central</source><creator>Zhang, Yin ; dan Li, Shao ; Zhang, Jun Xiu ; Liu, Yi ; Cui, Yi xin ; Yang, Min hui</creator><creatorcontrib>Zhang, Yin ; dan Li, Shao ; Zhang, Jun Xiu ; Liu, Yi ; Cui, Yi xin ; Yang, Min hui</creatorcontrib><description>Objective: Discussing the effects of Ziyinqingre prescription on the
level of airway resistance (Rrs), airway response threshold (Dmin),
airway conductance (sGrs) and the level of inflammatory cytokines
interleukin-4 (IL-4) and interferon-γ (IFN-γ) of the
bronchial hyper-responsiveness (BHR) cough patients. Method: 84
subjects diagnosed as BHR were randomly divided into 42 Chinese
Traditional medicine group and 42 control group. The Chinese
Traditional Medicine group received Ziyinqingre prescription twice a
day and the control group received 10mg Montelukast Sodium tablets once
a day for two weeks. Observe the clinical symptoms improvement and the
changes of the level of the Rrs, Dmin, sGrs and IL-4, IFN-γ.
Results: After receiving the medicine, the symptoms of the Chinese
medicine group were obviously alleviated, the outcome was more
satisfied than that of the control group. Compared with the control
group, the level of Dmin increased and sGrs level decreased more
obviously (P<0.05); the level of IL-4 decreased and IFN-γlevel
increased more obviously in the Chinese medicine group (P<0.05).
Conclusion: Ziyinqingre prescription can not only improve BHR
patients' symptoms, but reduce the level of bronchial
responsiveness, which proved a better curative effect of Chinese
medicine. The mechanism is probably due to relieving the airway
inflammation by keeping the balance between Th1 and Th2 cells.</description><identifier>ISSN: 0189-6016</identifier><identifier>EISSN: 2505-0044</identifier><identifier>DOI: 10.21010/ajtcam.v13i5.25</identifier><identifier>PMID: 28487911</identifier><language>eng</language><publisher>Nigeria: African Ethnomedicines Network</publisher><subject>Adolescent ; Adult ; bronchial hyper-responsiveness ; Bronchial Hyperreactivity - blood ; Bronchial Hyperreactivity - drug therapy ; Bronchial Hyperreactivity - physiopathology ; Bronchial Provocation Tests ; cough ; Cough - blood ; Cough - drug therapy ; Cough - physiopathology ; Drugs, Chinese Herbal - therapeutic use ; Female ; Humans ; Interferon-gamma - blood ; Interleukin-4 - blood ; Male ; Medicine, Chinese Traditional - methods ; Middle Aged ; Phytotherapy - methods ; therapeutic mechanism ; Treatment Outcome ; Young Adult ; Ziyinqingre prescription</subject><ispartof>African journal of traditional, complementary, and alternative medicines, 2016-01, Vol.13 (5), p.190-194</ispartof><rights>Copyright 2016 - African Journal of Traditional, Complementary and Alternative Medicines</rights><rights>Copyright: © 2016 Afr. J. Traditional Complementary and Alternative Medicines 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416640/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416640/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28487911$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Yin</creatorcontrib><creatorcontrib>dan Li, Shao</creatorcontrib><creatorcontrib>Zhang, Jun Xiu</creatorcontrib><creatorcontrib>Liu, Yi</creatorcontrib><creatorcontrib>Cui, Yi xin</creatorcontrib><creatorcontrib>Yang, Min hui</creatorcontrib><title>THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION</title><title>African journal of traditional, complementary, and alternative medicines</title><addtitle>Afr J Tradit Complement Altern Med</addtitle><description>Objective: Discussing the effects of Ziyinqingre prescription on the
level of airway resistance (Rrs), airway response threshold (Dmin),
airway conductance (sGrs) and the level of inflammatory cytokines
interleukin-4 (IL-4) and interferon-γ (IFN-γ) of the
bronchial hyper-responsiveness (BHR) cough patients. Method: 84
subjects diagnosed as BHR were randomly divided into 42 Chinese
Traditional medicine group and 42 control group. The Chinese
Traditional Medicine group received Ziyinqingre prescription twice a
day and the control group received 10mg Montelukast Sodium tablets once
a day for two weeks. Observe the clinical symptoms improvement and the
changes of the level of the Rrs, Dmin, sGrs and IL-4, IFN-γ.
Results: After receiving the medicine, the symptoms of the Chinese
medicine group were obviously alleviated, the outcome was more
satisfied than that of the control group. Compared with the control
group, the level of Dmin increased and sGrs level decreased more
obviously (P<0.05); the level of IL-4 decreased and IFN-γlevel
increased more obviously in the Chinese medicine group (P<0.05).
Conclusion: Ziyinqingre prescription can not only improve BHR
patients' symptoms, but reduce the level of bronchial
responsiveness, which proved a better curative effect of Chinese
medicine. The mechanism is probably due to relieving the airway
inflammation by keeping the balance between Th1 and Th2 cells.</description><subject>Adolescent</subject><subject>Adult</subject><subject>bronchial hyper-responsiveness</subject><subject>Bronchial Hyperreactivity - blood</subject><subject>Bronchial Hyperreactivity - drug therapy</subject><subject>Bronchial Hyperreactivity - physiopathology</subject><subject>Bronchial Provocation Tests</subject><subject>cough</subject><subject>Cough - blood</subject><subject>Cough - drug therapy</subject><subject>Cough - physiopathology</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Interferon-gamma - blood</subject><subject>Interleukin-4 - blood</subject><subject>Male</subject><subject>Medicine, Chinese Traditional - methods</subject><subject>Middle Aged</subject><subject>Phytotherapy - methods</subject><subject>therapeutic mechanism</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><subject>Ziyinqingre prescription</subject><issn>0189-6016</issn><issn>2505-0044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpVkcFvmzAUxq1p05q2u-80-bgLmQ22MZdJlLnBUgoMSKXsYhkwGxUJHZBK_e_rNW20Srb89N7v-2z5A-AzRksXI4y-6bu51rvlA_Y6unTpO7BwKaIOQoS8BwuEeeAwhNkZOJ-mO4Q8jl3_IzhzOeF-gPECHMpYQLvzMBObUkZQ3IbrTVjKNIFh8gPeiCgOE1ncQNsoc2EnyQpe5WkSxTJcw3ibidzJRZGlSSFvRSKKAkbpZhXDqy38Jbcy-WkVuYCZhaJcZv-sL8GHVveT-fRyXoDNtSij2FmnKxmFa6cilM9O0JIAk7ryOW5RQ5khjNm6MQHhnHqsYk1DcONXnLpaE6rbtm2MjxE3rNK1612A70ff-0O1M01t9vOoe3U_djs9PqpBd-rtZN_9Ub-HB0UJZowga_D1xWAc_h7MNKtdN9Wm7_XeDIdJ2Q8OMPIZDSyKjmg9DtM0mvZ0DUbqOS11TEs9p6VcaiVf_n_eSfAajwWWR6Dqhr7bmxNRj51Wr825tgsz7LneE0Ism9U</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Zhang, Yin</creator><creator>dan Li, Shao</creator><creator>Zhang, Jun Xiu</creator><creator>Liu, Yi</creator><creator>Cui, Yi xin</creator><creator>Yang, Min hui</creator><general>African Ethnomedicines Network</general><general>African Traditional Herbal Medicine Supporters Initiative (ATHMSI)</general><scope>RBI</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160101</creationdate><title>THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION</title><author>Zhang, Yin ; dan Li, Shao ; Zhang, Jun Xiu ; Liu, Yi ; Cui, Yi xin ; Yang, Min hui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b458t-9f4914cb781f0d56e466781de9488536b6dd41d7b852aa45afffde7108e6bac23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>bronchial hyper-responsiveness</topic><topic>Bronchial Hyperreactivity - blood</topic><topic>Bronchial Hyperreactivity - drug therapy</topic><topic>Bronchial Hyperreactivity - physiopathology</topic><topic>Bronchial Provocation Tests</topic><topic>cough</topic><topic>Cough - blood</topic><topic>Cough - drug therapy</topic><topic>Cough - physiopathology</topic><topic>Drugs, Chinese Herbal - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Interferon-gamma - blood</topic><topic>Interleukin-4 - blood</topic><topic>Male</topic><topic>Medicine, Chinese Traditional - methods</topic><topic>Middle Aged</topic><topic>Phytotherapy - methods</topic><topic>therapeutic mechanism</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><topic>Ziyinqingre prescription</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Yin</creatorcontrib><creatorcontrib>dan Li, Shao</creatorcontrib><creatorcontrib>Zhang, Jun Xiu</creatorcontrib><creatorcontrib>Liu, Yi</creatorcontrib><creatorcontrib>Cui, Yi xin</creatorcontrib><creatorcontrib>Yang, Min hui</creatorcontrib><collection>Bioline International</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>African journal of traditional, complementary, and alternative medicines</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Yin</au><au>dan Li, Shao</au><au>Zhang, Jun Xiu</au><au>Liu, Yi</au><au>Cui, Yi xin</au><au>Yang, Min hui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION</atitle><jtitle>African journal of traditional, complementary, and alternative medicines</jtitle><addtitle>Afr J Tradit Complement Altern Med</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>13</volume><issue>5</issue><spage>190</spage><epage>194</epage><pages>190-194</pages><issn>0189-6016</issn><eissn>2505-0044</eissn><abstract>Objective: Discussing the effects of Ziyinqingre prescription on the
level of airway resistance (Rrs), airway response threshold (Dmin),
airway conductance (sGrs) and the level of inflammatory cytokines
interleukin-4 (IL-4) and interferon-γ (IFN-γ) of the
bronchial hyper-responsiveness (BHR) cough patients. Method: 84
subjects diagnosed as BHR were randomly divided into 42 Chinese
Traditional medicine group and 42 control group. The Chinese
Traditional Medicine group received Ziyinqingre prescription twice a
day and the control group received 10mg Montelukast Sodium tablets once
a day for two weeks. Observe the clinical symptoms improvement and the
changes of the level of the Rrs, Dmin, sGrs and IL-4, IFN-γ.
Results: After receiving the medicine, the symptoms of the Chinese
medicine group were obviously alleviated, the outcome was more
satisfied than that of the control group. Compared with the control
group, the level of Dmin increased and sGrs level decreased more
obviously (P<0.05); the level of IL-4 decreased and IFN-γlevel
increased more obviously in the Chinese medicine group (P<0.05).
Conclusion: Ziyinqingre prescription can not only improve BHR
patients' symptoms, but reduce the level of bronchial
responsiveness, which proved a better curative effect of Chinese
medicine. The mechanism is probably due to relieving the airway
inflammation by keeping the balance between Th1 and Th2 cells.</abstract><cop>Nigeria</cop><pub>African Ethnomedicines Network</pub><pmid>28487911</pmid><doi>10.21010/ajtcam.v13i5.25</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0189-6016 |
| ispartof | African journal of traditional, complementary, and alternative medicines, 2016-01, Vol.13 (5), p.190-194 |
| issn | 0189-6016 2505-0044 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5416640 |
| source | PubMed Central |
| subjects | Adolescent Adult bronchial hyper-responsiveness Bronchial Hyperreactivity - blood Bronchial Hyperreactivity - drug therapy Bronchial Hyperreactivity - physiopathology Bronchial Provocation Tests cough Cough - blood Cough - drug therapy Cough - physiopathology Drugs, Chinese Herbal - therapeutic use Female Humans Interferon-gamma - blood Interleukin-4 - blood Male Medicine, Chinese Traditional - methods Middle Aged Phytotherapy - methods therapeutic mechanism Treatment Outcome Young Adult Ziyinqingre prescription |
| title | THE THERAPEUTIC EVALUATION AND MECHANISM ON TREATING BRONCHIAL HYPER-RESPONSIVENESS COUGH BY ZIYINQINGRE PRESCRIPTION |
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