Antioxidant and Synergistic Antidiabetic Activities of a Three-Plant Preparation Used in Cameroon Folk Medicine

Introduction. Several plant preparations like a mixture of aqueous extracts of Spilanthes africana; Portulaca oleracea; and Sida rhombifolia are currently utilized in Foumban (West Cameroon) to manage diabetes. The aim of this study is to investigate the antidiabetic property of the aqueous mixture...

Full description

Saved in:
Bibliographic Details
Published in:International scholarly research notices 2017, Vol.2017, p.9501675-7
Main Authors: Moukette, Bruno Moukette, Ama Moor, Vicky Jocelyne, Biapa Nya, Cacral Prosper, Nanfack, Pauline, Nzufo, Francine Tankeu, Kenfack, Marcel Azabji, Ngogang, Jeanne Yonkeu, Pieme, Constant Anatole
Format: Article
Language:English
Subjects:
Antioxidants
Biological products
Blood cholesterol
Diabetes
Enzymes
Flavonoids
Folk medicine
Insulin resistance
Lipid peroxidation
Lipids
Low density lipoproteins
Medicine
Oxidative stress
Phytochemicals
Polyphenols
Portulaca oleracea
Rodents
Sida rhombifolia
Spilanthes
Streptozocin
Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction. Several plant preparations like a mixture of aqueous extracts of Spilanthes africana; Portulaca oleracea; and Sida rhombifolia are currently utilized in Foumban (West Cameroon) to manage diabetes. The aim of this study is to investigate the antidiabetic property of the aqueous mixture of three plant extracts (1 : 1 : 1) on streptozotocin induced diabetes rats. Methods. Diabetes was induced to rats by intraperitoneal (i.p.) injection of streptozotocin (STZ) at a dose of 50 mg/kg b.w. The diabetic rats received different dosages of the mixture of extracts for 21 days and glibenclamide 6.5 mg/kg b.w. as positive control. Results. The results showed that the mixture of extracts significantly (p
ISSN:2356-7872
2356-7872
DOI:10.1155/2017/9501675