Paper-based plasma sanitizers

• Published in: Proceedings of the National Academy of Sciences - PNAS 2017-05, Vol.114 (20), p.5119-5124
• Main Authors: Xie, Jingjin, Chen, Qiang, Suresh, Poornima, Roy, Subrata, White, James F., Mazzeo, Aaron D.
• Format: Article
• Language: English
• Subjects: Activation; Aerosols; Antiinfectives and antibacterials; Biodegradability; Biodegradation; Coliforms; Compatibility; Contamination; Convection; Convection cooling; Deactivation; Devices; Dielectric barrier discharge; Dielectrics; E coli; Forced convection; Format; Fuels; Generators; Interfaces; Metallizing; Ozone; Physical Sciences; Plasma; Plasma generators; Porosity; Prosthetics; Robots; Sanitizers; Sensors; Skin; Substrates; Surface temperature; Temperature effects; Vacuum; Yeast
• ISSN: 0027-8424; 1091-6490
• DOI: 10.1073/pnas.1621203114

This work describes disposable plasma generators made from metallized paper. The fabricated plasma generators with layered and patterned sheets of paper provide a simple and flexible format for dielectric barrier discharge to create atmospheric plasma without an applied vacuum. The porosity of paper allows gas to permeate its bulk volume and fuel plasma, while plasma-induced forced convection cools the substrate. When electrically driven with oscillating peak-to-peak potentials of ±1 to ±10 kV, the paper-based devices produced both volume and surface plasmas capable of killing microbes. The plasma sanitizers deactivated greater than 99% of Saccharomyces cerevisiae and greater than 99.9% of Escherichia coli cells with 30 s of noncontact treatment. Characterization of plasma generated from the sanitizers revealed a detectable level of UV-C (1.9 nW·cm−2·nm−1), modest surface temperature (60 °C with 60 s of activation), and a high level of ozone (13 ppm with 60 s of activation). These results deliver insights into themechanisms and suitability of paper-based substrates for active antimicrobial sanitization with scalable, flexible sheets. In addition, this work shows how paper-based generators are conformable to curved surfaces, appropriate for kirigami-like “stretchy” structures, compatible with user interfaces, and suitable for sanitization of microbes aerosolized onto a surface. In general, these disposable plasma generators represent progress toward biodegradable devices based on flexible renewable materials, which may impact the future design of protective garments, skin-like sensors for robots or prosthetics, and user interfaces in contaminated environments.