Role of Plasma Fibrinogen in Diagnosis and Prediction of Short Term Outcome in Neonatal Sepsis

The study was carried out to determine the role of plasma fibrinogen in diagnosis of neonatal sepsis and to evaluate its role in predicting short term outcome. Sixty five neonates with clinical features suggestive of neonatal sepsis were included in this study. Seventy five neonates served as the co...

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Bibliographic Details
Published in:Indian journal of hematology & blood transfusion 2017-06, Vol.33 (2), p.195-199
Main Authors: Mitra, Piyali, Guha, Debasish, Nag, Shankha S., Mondal, Badal C., Dasgupta, Sayantan
Format: Article
Language:English
Subjects:
Blood Transfusion Medicine
Hematology
Human Genetics
Medical diagnosis
Medical prognosis
Medicine
Medicine & Public Health
Newborn babies
Oncology
Original
Original Article
Plasma
Proteins
Sepsis
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Summary:The study was carried out to determine the role of plasma fibrinogen in diagnosis of neonatal sepsis and to evaluate its role in predicting short term outcome. Sixty five neonates with clinical features suggestive of neonatal sepsis were included in this study. Seventy five neonates served as the control group. Plasma fibrinogen, prothrombin time, activated partial thromboplastin time and platelet counts were performed in all the neonates. Cut-off value of plasma fibrinogen for diagnosis of neonatal sepsis was determined with the help of receiver operating characteristic curve. Plasma fibrinogen level was found to be significantly higher among neonates with sepsis when compared to neonates in control group ( p  
ISSN:0971-4502
0974-0449
0974-0449
0971-4502
DOI:10.1007/s12288-016-0683-x