The impact of metformin use on survival in kidney cancer patients with diabetes: a meta-analysis

Purpose The effects of metformin on the prognosis of kidney cancer patients with diabetes are in controversial. The present study is conducted to classify the association of metformin use with the survival of patients with kidney cancer. Methods Electronic databases, namely PubMed and Web of Science...

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Bibliographic Details
Published in:International urology and nephrology 2017-06, Vol.49 (6), p.975-981
Main Authors: Li, Yang, Hu, Liyi, Xia, Qinghong, Yuan, Yongqiang, Mi, Yonghua
Format: Article
Language:English
Subjects:
Antidiabetics
Carcinoma, Renal Cell - complications
Carcinoma, Renal Cell - mortality
Death
Diabetes
Diabetes mellitus
Diabetes Mellitus - drug therapy
Disease-Free Survival
Humans
Hypoglycemic Agents - therapeutic use
Kidney cancer
Kidney Neoplasms - complications
Kidney Neoplasms - mortality
Medical prognosis
Medicine
Medicine & Public Health
Meta-analysis
Metformin
Metformin - therapeutic use
Nephrology
Prognosis
Renal cell carcinoma
Statistical analysis
Survival
Survival Rate
Urology
Urology - Original Paper
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Summary:Purpose The effects of metformin on the prognosis of kidney cancer patients with diabetes are in controversial. The present study is conducted to classify the association of metformin use with the survival of patients with kidney cancer. Methods Electronic databases, namely PubMed and Web of Science, were used to search the eligible studies up to December, 2016. Pooled hazard ratio (HR) and its corresponding 95% confidence interval (95% CI) were calculated. It was considered as statistically significant when P value was
ISSN:0301-1623
1573-2584
DOI:10.1007/s11255-017-1548-4