Serum albumin predicts survival in patients with hilar cholangiocarcinoma

Background and aims: Hilar cholangiocarcinoma is a devastating malignancy with incidence varying by geography and other risk factors. Rapid progression of disease and delays in diagnosis restrict the number of patients eligible for curative therapy. The objective of this study was to determine progn...

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Published in:Gastroenterology report 2017-02, Vol.5 (1), p.62-66
Main Authors: Waghray, Abhijeet, Sobotka, Anastasia, Marrero, Carlos Romero, Estfan, Bassam, Aucejo, Federico, Narayanan Menon, KV
Format: Article
Language:English
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Summary:Background and aims: Hilar cholangiocarcinoma is a devastating malignancy with incidence varying by geography and other risk factors. Rapid progression of disease and delays in diagnosis restrict the number of patients eligible for curative therapy. The objective of this study was to determine prognostic factors of overall survival in all patients presenting with hilar cholangiocarcinoma. Methods: All adult patients with histologically confirmed hilar cholangiocarcinoma from 2003 to 2013 were evaluated for predictors of survival using demographic factors, laboratory data, symptoms and radiological characteristics at presentation. Results: A total of 116 patients were identified to have pathological diagnosis of hilar cholangiocarcinoma and were included in the analysis. Patients with a serum albumin level >3.0 g/dL (P 
ISSN:2052-0034
2052-0034
DOI:10.1093/gastro/gow021