Efficacy of ivermectin, closantel and fenbendazole against gastrointestinal nematodes of sheep in Kashmir valley

• Published in: Journal of parasitic diseases 2017-06, Vol.41 (2), p.380-382
• Main Authors: Tramboo, S. R., Shahardar, R. A., Allaie, I. M., Wani, Z. A., Abbas, Maria
• Format: Article
• Language: English
• Subjects: Health Promotion and Disease Prevention; Infectious Diseases; Intestinal parasites; Ivermectin; Medicine; Medicine & Public Health; Original; Original Article; Sheep
• ISSN: 0971-7196; 0975-0703
• DOI: 10.1007/s12639-016-0810-5

The present work was undertaken to evaluate the therapeutic efficacy of ivermectin, closantel and fenbendazole under field conditions against Gastrointestinal Nematodes (GIN) of cross bred merino sheep in Budgam area of Kashmir Valley. A total of 115 sheep having Egg per gram of faeces (EPG) greater than or equal to 150 (mean EPG 258.89) were selected. The animals were randomly divided into four groups comprising of 30 animals each in three treatment groups (ivermectin, closantel and fenbendazole) and twenty-five in fourth untreated infected control group. Faecal samples from the selected animals were collected on day ‘0’ pre treatment and on days 8th and 14th post treatment. Based on Faecal Egg Count Reduction Test (FECRT), ivermectin was found to be 98.80 % effective against strongyles on 8th day post treatment, however an efficacy of 100 % was seen against strongyle worms on 14th day post treatment. 98.80 and 100 % efficacy was observed on day 8th post treatment against strongyles in case of closantel and fenbendazole respectively, however efficacy decreased to 97.60 and 98.8 % respectively on 14th day post treatment. There was no evidence of development of resistance by GIN of cross bred merino sheep in District Budgam of Kashmir Valley to ivermectin, closantel and fenbendazole.