Diagnostic accuracy of diffusion-weighted whole-body imaging with background body signal suppression/T2-weighted image fusion for the detection of abdominal solid cancer

Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) images show significant contrast for cancer tissues against non-cancerous tissues. Fusion of a DWIBS and a T2-weighted image (DWIBS/T2) can be used to obtain functional, as well as anatomic, information. In the pre...

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Bibliographic Details
Published in:Experimental and therapeutic medicine 2017-06, Vol.13 (6), p.3509-3515
Main Authors: Tomizawa, Minoru, Shinozaki, Fuminobu, Fugo, Kazunori, Tanaka, Satomi, Sunaoshi, Takafumi, Kano, Daisuke, Sugiyama, Eriko, Shite, Misaki, Haga, Ryouta, Fukamizu, Yoshiya, Fujita, Toshiyuki, Kagayama, Satoshi, Hasegawa, Rumiko, Togawa, Akira, Shirai, Yoshinori, Ichiki, Noboru, Oshima, Yuji, Koike, Naoto, Toshimitsu, Yasuko, Motoyoshi, Yasufumi, Sugiyama, Takao, Yamamoto, Shigenori, Kishimoto, Takashi, Ishige, Naoki
Format: Article
Language:English
Subjects:
Abdomen
Breast cancer
Committees
Liver cancer
Lymphoma
Medical diagnosis
Medical imaging
Metastasis
NMR
Nuclear magnetic resonance
Pancreatic cancer
Patients
Respiration
Tumors
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Summary:Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) images show significant contrast for cancer tissues against non-cancerous tissues. Fusion of a DWIBS and a T2-weighted image (DWIBS/T2) can be used to obtain functional, as well as anatomic, information. In the present study, the performance of DWIBS/T2 in the diagnosis of abdominal solid cancer was evaluated. The records of 14 patients were retrospectively analyzed [5 patients with hepatocellular carcinoma (HCC), 4 with metastatic liver cancer, 3 with pancreatic cancer, 1 with renal cellular carcinoma and 1 with malignant lymphoma of the para-aortic lymph node]. T1WI and T2WI scans did not detect pancreatic cancer in certain cases, whereas DWIs and DWIBS/T2 clearly demonstrated pancreatic cancer in all cases. In addition, metastatic liver cancer and HCC were successfully detected with abdominal US and CECT; however, US did not detect pancreatic cancer in 1 case, while CECT and DWIBS/T2 detected pancreatic cancer in all cases. In conclusion, the diagnostic performance of DWIBS/T2 was the same as that of abdominal US and CECT in detecting primary and metastatic liver cancer. DWIBS/T2 enabled the diagnosis of pancreatic cancer in cases where it was not detected with US, T1WI or T2WI.
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2017.4432