Comparison of hand-assisted laparoscopic surgery (HALS) and conventional laparotomy in patients with colorectal cancer: Final results from a single center

In recent years, the use of laparoscopic surgery has been expanded to include radical curative resection. In a previous study, 212 patients with primary colorectal cancer (stages I-III) underwent radical curative resection by hand-assisted laparoscopic surgery (HALS) (n=98) or conventional laparotom...

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Bibliographic Details
Published in:Oncology letters 2017-06, Vol.13 (6), p.4953-4958
Main Authors: Tajima, Takayuki, Mukai, Masaya, Yokoyama, Daiki, Higami, Shigeo, Uda, Shuji, Hasegawa, Sayuri, Nomura, Eiji, Sadahiro, Sotaro, Yasuda, Seiei, Makuuchi, Hiroyasu
Format: Article
Language:English
Subjects:
Age
Care and treatment
Chemotherapy
Colorectal cancer
Comparative analysis
Development and progression
Laparoscopic surgery
Laparoscopy
Medical prognosis
Metastasis
Surgery
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Summary:In recent years, the use of laparoscopic surgery has been expanded to include radical curative resection. In a previous study, 212 patients with primary colorectal cancer (stages I-III) underwent radical curative resection by hand-assisted laparoscopic surgery (HALS) (n=98) or conventional laparotomy (CL) (n=114) and were compared with respect to 3-year relapse-free survival (3Y-RFS) and 3-year overall survival (3Y-OS). The study included 210/212 patients who were followed up to 5 years, including 96 patients who underwent HALS and 114 treated with CL. The two groups were matched for stage, clinical background, and postoperative management. Patient characteristics were compared and the 5Y-RFS and 5Y-OS were determined. The 5-year follow-up rate was 97.6%. In stage I-III patients, 5Y-RFS and 5Y-OS showed no significant differences between HALS and CL. The patients with stage I disease accounted for 41.7% (40/96) of the patients undergoing HALS, while stage I patients only accounted for 23.7% (27/114) of the patients undergoing CL, and the difference was significant (P=0.005). Stage II patients undergoing CL were older than those treated with HALS (P=0.017). However, there were no differences in the characteristics of stage III patients undergoing HALS or CL. In conclusion, HALS achieved a similar survival to CL in patients with stage I to III colorectal cancer. Compared with CL, HALS was performed more safely and achieved superior cosmetic results.
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2017.6035