Biocompatibility and Corrosion Protection Behaviour of Hydroxyapatite Sol-Gel-Derived Coatings on Ti6Al4V Alloy

The aim of this work was to prepare hydroxyapatite coatings (HAp) by a sol-gel method on Ti6Al4V alloy and to study the bioactivity, biocompatibility and corrosion protection behaviour of these coatings in presence of simulated body fluids (SBFs). Thermogravimetric/Differential Thermal Analyses (TG/...

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Bibliographic Details
Published in:Materials 2017-01, Vol.10 (2), p.94
Main Authors: El Hadad, Amir A, Peón, Eduardo, García-Galván, Federico R, Barranco, Violeta, Parra, Juan, Jiménez-Morales, Antonia, Galván, Juan Carlos
Format: Article
Language:English
Subjects:
Biocompatibility
Biological activity
Biomedical materials
Body fluids
Corrosion
Corrosion prevention
Crystallites
Degree of crystallinity
Differential thermal analysis
Differential thermogravimetric analysis
Electrochemical impedance spectroscopy
Functional groups
Hydroxyapatite
In vitro methods and tests
Inductively coupled plasma
Morphology
Phase transitions
Protective coatings
Sol-gel processes
Surgical implants
Titanium base alloys
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Summary:The aim of this work was to prepare hydroxyapatite coatings (HAp) by a sol-gel method on Ti6Al4V alloy and to study the bioactivity, biocompatibility and corrosion protection behaviour of these coatings in presence of simulated body fluids (SBFs). Thermogravimetric/Differential Thermal Analyses (TG/DTA) and X-ray Diffraction (XRD) have been applied to obtain information about the phase transformations, mass loss, identification of the phases developed, crystallite size and degree of crystallinity of the obtained HAp powders. Fourier Transformer Infrared Spectroscopy (FTIR) has been utilized for studying the functional groups of the prepared structures. The surface morphology of the resulting HAp coatings was studied by Scanning Electron Microscopy (SEM). The bioactivity was evaluated by soaking the HAp-coatings/Ti6Al4V system in Kokubo's Simulated Body Fluid (SBF) applying Inductively Coupled Plasma (ICP) spectrometry. 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) and Alamar blue cell viability assays were used to study the biocompatibility. Finally, the corrosion behaviour of HAp-coatings/Ti6Al4V system was researched by means of Electrochemical Impedance Spectroscopy (EIS). The obtained results showed that the prepared powders were nanocrystalline HAp with little deviations from that present in the human bone. All the prepared HAp coatings deposited on Ti6Al4V showed well-behaved biocompatibility, good bioactivity and corrosion protection properties.
ISSN:1996-1944
1996-1944
DOI:10.3390/ma10020094