Motion management strategies and technical issues associated with stereotactic body radiotherapy of thoracic and upper abdominal tumors: A review from NRG oncology

The efficacy of stereotactic body radiotherapy (SBRT) has been well demonstrated. However, it presents unique challenges for accurate planning and delivery especially in the lungs and upper abdomen where respiratory motion can be significantly confounding accurate targeting and avoidance of normal t...

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Bibliographic Details
Published in:Medical physics (Lancaster) 2017-06, Vol.44 (6), p.2595-2612
Main Authors: Brandner, Edward D., Chetty, Indrin J., Giaddui, Tawfik G., Xiao, Ying, Huq, M. Saiful
Format: Article
Language:English
Subjects:
abdomen
Abdominal Neoplasms - radiotherapy
gating
Humans
Lung
Lung Neoplasms - radiotherapy
Motion
Radiosurgery
respiratory motion
SBRT
stereotactic body radiotherapy
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Summary:The efficacy of stereotactic body radiotherapy (SBRT) has been well demonstrated. However, it presents unique challenges for accurate planning and delivery especially in the lungs and upper abdomen where respiratory motion can be significantly confounding accurate targeting and avoidance of normal tissues. In this paper, we review the current literature on SBRT for lung and upper abdominal tumors with particular emphasis on addressing respiratory motion and its affects. We provide recommendations on strategies to manage motion for different, patient‐specific situations. Some of the recommendations will potentially be adopted to guide clinical trial protocols.
ISSN:0094-2405
2473-4209
DOI:10.1002/mp.12227