A case-control study to assess the effectiveness of pertussis vaccination during pregnancy on newborns, Valencian community, Spain, 1 March 2015 to 29 February 2016

In the Valencian Community (Spain), the programme of maternal pertussis vaccination during pregnancy started in January 2015. The objective of this study was to estimate in this region the vaccine effectiveness (VE) in protecting newborns against laboratory-confirmed pertussis infection. A matched c...

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Bibliographic Details
Published in:Euro surveillance : bulletin européen sur les maladies transmissibles 2017-06, Vol.22 (22), p.2
Main Authors: Bellido-Blasco, Juan, Guiral-Rodrigo, Silvia, Míguez-Santiyán, Ana, Salazar-Cifre, Antonio, González-Morán, Francisco
Format: Article
Language:English
Subjects:
Antibodies, Bacterial - blood
Bordetella pertussis - immunology
Bordetella pertussis - isolation & purification
Case-Control Studies
Effectiveness
Female
Humans
Immunization
Immunization Schedule
Infant, Newborn
Infectious Disease Transmission, Vertical - prevention & control
Male
Newborn babies
Pertussis Vaccine - administration & dosage
Pertussis Vaccine - immunology
Pregnancy
Pregnancy Complications, Infectious - prevention & control
Real-Time Polymerase Chain Reaction
Spain - epidemiology
Vaccination
Whooping cough
Whooping Cough - epidemiology
Whooping Cough - immunology
Whooping Cough - prevention & control
Women
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Summary:In the Valencian Community (Spain), the programme of maternal pertussis vaccination during pregnancy started in January 2015. The objective of this study was to estimate in this region the vaccine effectiveness (VE) in protecting newborns against laboratory-confirmed pertussis infection. A matched case-control study was undertaken in the period between 1 March 2015 and 29 February 2016. Twenty-two cases and 66 controls (+/- 15 days of age difference) were included in the study. Cases were non-vaccinated infants 
ISSN:1560-7917
1025-496X
1560-7917
DOI:10.2807/1560-7917.ES.2017.22.22.30545