Loading…

Minimally invasive thalamic hematoma drainage can improve the six-month outcome of thalamic hemorrhage

Objective To explore predictors of the 6-month clinical outcome ofthalamic hemorrhage, and evaluate if minimally invasive thalamic hematoma drainage (THD) could improve its prognosis. Methods A total of 54 patients with spontaneous thalamic hemorrhage were evaluated retrospectively. Clinical data, i...

Full description

Saved in:
Bibliographic Details
Published in:Journal of geriatric cardiology : JGC 2017-04, Vol.14 (4), p.266-273
Main Authors: Liu, Wen-Ming, Zhang, Xue-Guang, Zhang, Ze-Li, Li, Gang, Huang, Qi-Bing
Format: Article
Language:English
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 273
container_issue 4
container_start_page 266
container_title Journal of geriatric cardiology : JGC
container_volume 14
creator Liu, Wen-Ming
Zhang, Xue-Guang
Zhang, Ze-Li
Li, Gang
Huang, Qi-Bing
description Objective To explore predictors of the 6-month clinical outcome ofthalamic hemorrhage, and evaluate if minimally invasive thalamic hematoma drainage (THD) could improve its prognosis. Methods A total of 54 patients with spontaneous thalamic hemorrhage were evaluated retrospectively. Clinical data, including demographics, stroke risk factors, neuroimaging variables, Glasgow Coma Score (GCS) on admission, surgical strategy, and outcome, were collected. Clinical outcome was assessed using a modified Rankin Scale, six months after onset. Univariate analysis and multivariate logistic regression analysis were performed to determine predictors of a poor outcome. Results Conservative treatnaent was performed for five patients (9.3%), external ventricular drainage (EVD) for 20 patients (37.0%), THD for four patients (7.4%), and EVD combined with THD for 25 patients (46.3%). At six months after onset, 21 (38.9%) patients achieved a favorable outcome, while 33 (61.1%) had a poor outcome. In the univariate analysis, predictors of poor 6-month outcome were lower GCS on admis- sion (P = 0.001), larger hematoma volume (P 〈 0.001), midline shift (P = 0.035), acute hydrocephalus (P = 0.039), and no THD (P = 0.037). The independent predictors of poor outcome, according to the multivariate logistic regression analysis, were no THD and larger hematoma volume. Conclusions Minimally invasive THD, which removes most of the hematoma within a few days, with limited damage to perihematomal brain tissue, improved the 6-month outcome of thalamic hemorrhage. Thus, THD can be widely applied to treat patients with thalamic hemorrhage.
doi_str_mv 10.11909/j.issn.1671-5411.2017.04.006
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5483596</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>672926609</cqvip_id><sourcerecordid>1915343748</sourcerecordid><originalsourceid>FETCH-LOGICAL-c293t-b2c11dfb936d488ab7bdbc27b45fb3cb54b34aa4daba43165aec287e0e308e1d3</originalsourceid><addsrcrecordid>eNpVkEtLxDAUhbNQHB39CxIEwU1r3m03gogvUNzoutyk6TTSJGPTGfTfW5xx0NWFe79zDucidE5JTmlFqsv33KUUcqoKmklBac4ILXIickLUHjrc7WfoKKV3QmQpBTtAM1YqxQslD1H77ILz0Pdf2IU1JLe2eOygB-8M7qyHMXrAzQAuwMJiAwE7vxziD2Zxcp-Zj2HscFyNJnqLY_tPH4ehm4THaL-FPtmT7Zyjt7vb15uH7Onl_vHm-ikzrOJjppmhtGl1xVUjyhJ0oRttWKGFbDU3WgrNBYBoQIPgVEmwhpWFJZaT0tKGz9HVxne50t42xoZxgL5eDlPH4auO4Or_l-C6ehHXtRQll5WaDC62BkP8WNk01t4lY_sego2rVNOKSi54MeFzdPo3axfy-9wJONsApoth8eHCYseoglVMKVLxb8_NjSA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1915343748</pqid></control><display><type>article</type><title>Minimally invasive thalamic hematoma drainage can improve the six-month outcome of thalamic hemorrhage</title><source>PubMed Central(OA)</source><creator>Liu, Wen-Ming ; Zhang, Xue-Guang ; Zhang, Ze-Li ; Li, Gang ; Huang, Qi-Bing</creator><creatorcontrib>Liu, Wen-Ming ; Zhang, Xue-Guang ; Zhang, Ze-Li ; Li, Gang ; Huang, Qi-Bing</creatorcontrib><description>Objective To explore predictors of the 6-month clinical outcome ofthalamic hemorrhage, and evaluate if minimally invasive thalamic hematoma drainage (THD) could improve its prognosis. Methods A total of 54 patients with spontaneous thalamic hemorrhage were evaluated retrospectively. Clinical data, including demographics, stroke risk factors, neuroimaging variables, Glasgow Coma Score (GCS) on admission, surgical strategy, and outcome, were collected. Clinical outcome was assessed using a modified Rankin Scale, six months after onset. Univariate analysis and multivariate logistic regression analysis were performed to determine predictors of a poor outcome. Results Conservative treatnaent was performed for five patients (9.3%), external ventricular drainage (EVD) for 20 patients (37.0%), THD for four patients (7.4%), and EVD combined with THD for 25 patients (46.3%). At six months after onset, 21 (38.9%) patients achieved a favorable outcome, while 33 (61.1%) had a poor outcome. In the univariate analysis, predictors of poor 6-month outcome were lower GCS on admis- sion (P = 0.001), larger hematoma volume (P 〈 0.001), midline shift (P = 0.035), acute hydrocephalus (P = 0.039), and no THD (P = 0.037). The independent predictors of poor outcome, according to the multivariate logistic regression analysis, were no THD and larger hematoma volume. Conclusions Minimally invasive THD, which removes most of the hematoma within a few days, with limited damage to perihematomal brain tissue, improved the 6-month outcome of thalamic hemorrhage. Thus, THD can be widely applied to treat patients with thalamic hemorrhage.</description><identifier>ISSN: 1671-5411</identifier><identifier>DOI: 10.11909/j.issn.1671-5411.2017.04.006</identifier><identifier>PMID: 28663765</identifier><language>eng</language><publisher>China: Science Press</publisher><subject>logistic回归分析 ; 丘脑 ; 临床资料 ; 单因素分析 ; 引流 ; 脑出血 ; 血肿 ; 预后</subject><ispartof>Journal of geriatric cardiology : JGC, 2017-04, Vol.14 (4), p.266-273</ispartof><rights>Institute of Geriatric Cardiology 2017</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/88644X/88644X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483596/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483596/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28663765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Wen-Ming</creatorcontrib><creatorcontrib>Zhang, Xue-Guang</creatorcontrib><creatorcontrib>Zhang, Ze-Li</creatorcontrib><creatorcontrib>Li, Gang</creatorcontrib><creatorcontrib>Huang, Qi-Bing</creatorcontrib><title>Minimally invasive thalamic hematoma drainage can improve the six-month outcome of thalamic hemorrhage</title><title>Journal of geriatric cardiology : JGC</title><addtitle>Journal of Geriatric Cardiology</addtitle><description>Objective To explore predictors of the 6-month clinical outcome ofthalamic hemorrhage, and evaluate if minimally invasive thalamic hematoma drainage (THD) could improve its prognosis. Methods A total of 54 patients with spontaneous thalamic hemorrhage were evaluated retrospectively. Clinical data, including demographics, stroke risk factors, neuroimaging variables, Glasgow Coma Score (GCS) on admission, surgical strategy, and outcome, were collected. Clinical outcome was assessed using a modified Rankin Scale, six months after onset. Univariate analysis and multivariate logistic regression analysis were performed to determine predictors of a poor outcome. Results Conservative treatnaent was performed for five patients (9.3%), external ventricular drainage (EVD) for 20 patients (37.0%), THD for four patients (7.4%), and EVD combined with THD for 25 patients (46.3%). At six months after onset, 21 (38.9%) patients achieved a favorable outcome, while 33 (61.1%) had a poor outcome. In the univariate analysis, predictors of poor 6-month outcome were lower GCS on admis- sion (P = 0.001), larger hematoma volume (P 〈 0.001), midline shift (P = 0.035), acute hydrocephalus (P = 0.039), and no THD (P = 0.037). The independent predictors of poor outcome, according to the multivariate logistic regression analysis, were no THD and larger hematoma volume. Conclusions Minimally invasive THD, which removes most of the hematoma within a few days, with limited damage to perihematomal brain tissue, improved the 6-month outcome of thalamic hemorrhage. Thus, THD can be widely applied to treat patients with thalamic hemorrhage.</description><subject>logistic回归分析</subject><subject>丘脑</subject><subject>临床资料</subject><subject>单因素分析</subject><subject>引流</subject><subject>脑出血</subject><subject>血肿</subject><subject>预后</subject><issn>1671-5411</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpVkEtLxDAUhbNQHB39CxIEwU1r3m03gogvUNzoutyk6TTSJGPTGfTfW5xx0NWFe79zDucidE5JTmlFqsv33KUUcqoKmklBac4ILXIickLUHjrc7WfoKKV3QmQpBTtAM1YqxQslD1H77ILz0Pdf2IU1JLe2eOygB-8M7qyHMXrAzQAuwMJiAwE7vxziD2Zxcp-Zj2HscFyNJnqLY_tPH4ehm4THaL-FPtmT7Zyjt7vb15uH7Onl_vHm-ikzrOJjppmhtGl1xVUjyhJ0oRttWKGFbDU3WgrNBYBoQIPgVEmwhpWFJZaT0tKGz9HVxne50t42xoZxgL5eDlPH4auO4Or_l-C6ehHXtRQll5WaDC62BkP8WNk01t4lY_sego2rVNOKSi54MeFzdPo3axfy-9wJONsApoth8eHCYseoglVMKVLxb8_NjSA</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Liu, Wen-Ming</creator><creator>Zhang, Xue-Guang</creator><creator>Zhang, Ze-Li</creator><creator>Li, Gang</creator><creator>Huang, Qi-Bing</creator><general>Science Press</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170401</creationdate><title>Minimally invasive thalamic hematoma drainage can improve the six-month outcome of thalamic hemorrhage</title><author>Liu, Wen-Ming ; Zhang, Xue-Guang ; Zhang, Ze-Li ; Li, Gang ; Huang, Qi-Bing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c293t-b2c11dfb936d488ab7bdbc27b45fb3cb54b34aa4daba43165aec287e0e308e1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>logistic回归分析</topic><topic>丘脑</topic><topic>临床资料</topic><topic>单因素分析</topic><topic>引流</topic><topic>脑出血</topic><topic>血肿</topic><topic>预后</topic><toplevel>online_resources</toplevel><creatorcontrib>Liu, Wen-Ming</creatorcontrib><creatorcontrib>Zhang, Xue-Guang</creatorcontrib><creatorcontrib>Zhang, Ze-Li</creatorcontrib><creatorcontrib>Li, Gang</creatorcontrib><creatorcontrib>Huang, Qi-Bing</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of geriatric cardiology : JGC</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Wen-Ming</au><au>Zhang, Xue-Guang</au><au>Zhang, Ze-Li</au><au>Li, Gang</au><au>Huang, Qi-Bing</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Minimally invasive thalamic hematoma drainage can improve the six-month outcome of thalamic hemorrhage</atitle><jtitle>Journal of geriatric cardiology : JGC</jtitle><addtitle>Journal of Geriatric Cardiology</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>14</volume><issue>4</issue><spage>266</spage><epage>273</epage><pages>266-273</pages><issn>1671-5411</issn><abstract>Objective To explore predictors of the 6-month clinical outcome ofthalamic hemorrhage, and evaluate if minimally invasive thalamic hematoma drainage (THD) could improve its prognosis. Methods A total of 54 patients with spontaneous thalamic hemorrhage were evaluated retrospectively. Clinical data, including demographics, stroke risk factors, neuroimaging variables, Glasgow Coma Score (GCS) on admission, surgical strategy, and outcome, were collected. Clinical outcome was assessed using a modified Rankin Scale, six months after onset. Univariate analysis and multivariate logistic regression analysis were performed to determine predictors of a poor outcome. Results Conservative treatnaent was performed for five patients (9.3%), external ventricular drainage (EVD) for 20 patients (37.0%), THD for four patients (7.4%), and EVD combined with THD for 25 patients (46.3%). At six months after onset, 21 (38.9%) patients achieved a favorable outcome, while 33 (61.1%) had a poor outcome. In the univariate analysis, predictors of poor 6-month outcome were lower GCS on admis- sion (P = 0.001), larger hematoma volume (P 〈 0.001), midline shift (P = 0.035), acute hydrocephalus (P = 0.039), and no THD (P = 0.037). The independent predictors of poor outcome, according to the multivariate logistic regression analysis, were no THD and larger hematoma volume. Conclusions Minimally invasive THD, which removes most of the hematoma within a few days, with limited damage to perihematomal brain tissue, improved the 6-month outcome of thalamic hemorrhage. Thus, THD can be widely applied to treat patients with thalamic hemorrhage.</abstract><cop>China</cop><pub>Science Press</pub><pmid>28663765</pmid><doi>10.11909/j.issn.1671-5411.2017.04.006</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1671-5411
ispartof Journal of geriatric cardiology : JGC, 2017-04, Vol.14 (4), p.266-273
issn 1671-5411
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5483596
source PubMed Central(OA)
subjects logistic回归分析
丘脑
临床资料
单因素分析
引流
脑出血
血肿
预后
title Minimally invasive thalamic hematoma drainage can improve the six-month outcome of thalamic hemorrhage
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T15%3A37%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Minimally%20invasive%20thalamic%20hematoma%20drainage%20can%20improve%20the%20six-month%20outcome%20of%20thalamic%20hemorrhage&rft.jtitle=Journal%20of%20geriatric%20cardiology%20:%20JGC&rft.au=Liu,%20Wen-Ming&rft.date=2017-04-01&rft.volume=14&rft.issue=4&rft.spage=266&rft.epage=273&rft.pages=266-273&rft.issn=1671-5411&rft_id=info:doi/10.11909/j.issn.1671-5411.2017.04.006&rft_dat=%3Cproquest_pubme%3E1915343748%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c293t-b2c11dfb936d488ab7bdbc27b45fb3cb54b34aa4daba43165aec287e0e308e1d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1915343748&rft_id=info:pmid/28663765&rft_cqvip_id=672926609&rfr_iscdi=true