Photobiomodulation reduces drusen volume and improves visual acuity and contrast sensitivity in dry age‐related macular degeneration

Purpose To evaluate the efficacy of photobiomodulation (PBM) treatment for patients with dry age‐related macular degeneration (AMD). Methods Assessments on 42 eyes with dry AMD (age related eye disease study (AREDS) 2–4) were conducted. Multiwavelength light emitting diode (LED) light comprising of...

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Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2017-06, Vol.95 (4), p.e270-e277
Main Authors: Merry, Graham F., Munk, Marion R., Dotson, Robert S., Walker, Michael G., Devenyi, Robert G.
Format: Article
Language:English
Subjects:
Acuity
Age
Aged
Aged, 80 and over
age‐related macular degeneration
contrast
Contrast Sensitivity
drusen
Drying
Eye
Female
Follow-Up Studies
Functional anatomy
Humans
I.R. radiation
Laser Therapy - methods
Light effects
Light therapy
Macular degeneration
Macular Degeneration - complications
Macular Degeneration - diagnosis
Macular Degeneration - physiopathology
Male
Near infrared radiation
Original
photobiomodulation
Pilot Projects
Retina
Retina - physiopathology
Retinal Drusen - diagnosis
Retinal Drusen - etiology
Retinal Drusen - surgery
Retrospective Studies
Sensitivity
Tomography, Optical Coherence
Treatment Outcome
Visual Acuity
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Summary:Purpose To evaluate the efficacy of photobiomodulation (PBM) treatment for patients with dry age‐related macular degeneration (AMD). Methods Assessments on 42 eyes with dry AMD (age related eye disease study (AREDS) 2–4) were conducted. Multiwavelength light emitting diode (LED) light comprising of yellow (590 nm), red (670 nm) and near‐infrared (790 nm) bandwidths was applied to subjects’ eyes for a treatment course of 3 weeks. Outcome measures were changes in best‐corrected visual acuity (BCVA), contrast sensitivity (CS), drusen volume and central drusen thickness. Results Significant improvement in mean BCVA of 5.90 letters (p 
ISSN:1755-375X
1755-3768
DOI:10.1111/aos.13354