Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases

Health promotion strategies and lifestyle changes are important in disease prevention. Oral health has received a large amount of attention previously as it is a fundamental component of general health and it contributes to the quality of life. Therefore, the study of associations between diet, heal...

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Bibliographic Details
Published in:Experimental and therapeutic medicine 2017-07, Vol.14 (1), p.3-9
Main Authors: Perrone, Donatella, Fuggetta, Maria Pia, Ardito, Fatima, Cottarelli, Andrea, De Filippis, Anna, Ravagnan, Giampietro, De Maria, Salvatore, Lo Muzio, Lorenzo
Format: Article
Language:English
Subjects:
Apoptosis
Arthritis
Bioavailability
Cancer therapies
Cardiovascular disease
Cell cycle
Chronic illnesses
Clinical trials
Diabetes
Disease prevention
Functional foods & nutraceuticals
Health promotion
Kinases
Nutrition research
Oral cancer
Oral diseases
Oral hygiene
Oxidative stress
Polyphenols
Review
Squamous cell carcinoma
Studies
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Summary:Health promotion strategies and lifestyle changes are important in disease prevention. Oral health has received a large amount of attention previously as it is a fundamental component of general health and it contributes to the quality of life. Therefore, the study of associations between diet, health and the presence of bioactive compounds in food is receiving a substantial amount of attention. In the present review the effects and targets of a natural polyohenolic stilbenoid compound; resveratrol (3,5,4'-trihydroxystilbene; RSV) is assessed, and the future prospects for RSV in promoting oral health are considered. RSV is a phytoalexin, synthesized by a wide range of plants and abundantly extracted in grape skin, it has been purported to exert a multiplicity of anti-inflammatory, anti-viral, anti-microbial, estrogenic, anticancer, cardioprotective, neuroprotective and immunomodulatory functions. In this review, following an introduction documenting the biochemistry of RSV and RSV glucosides, the bioavailability and pharmacokinetics of RSV are described. Considering its multiple properties, the present review has focused on the potential benefits of RSV as an antioxidant and chemopreventive agent.
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2017.4472