Intrathoracic malignant peripheral nerve sheath tumor with poor outcome: a case report

We report a case of intrathoracic malignant peripheral nerve sheath tumor in a 65-year old woman revealed after a few-month history of progressive dyspnea, appetite and body mass loss. The chest magnetic resonance (MR) examination revealed the presence of a large tumor occupying the mediastinum and...

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Bibliographic Details
Published in:Biomolecules & biomedicine 2010-11, Vol.10 (4), p.328-330
Main Authors: Kolarov, Violeta, Stanić, Jelena, Eri, Zivka, Zvezdin, Biljana, Kojičić, Marija, Hromis, Sanja
Format: Article
Language:English
Subjects:
Aged
Anesthesia - methods
Biopsy - methods
Fatal Outcome
Female
Humans
Lung - pathology
magnetic resonance imaging
Magnetic Resonance Imaging - methods
malignant peripheral nerve sheath tumor
Mediastinal Neoplasms - diagnosis
Mediastinal Neoplasms - therapy
mediastinum
Mediastinum - pathology
Nerve Sheath Neoplasms - diagnosis
Nerve Sheath Neoplasms - therapy
Peripheral Nerves - pathology
Pulmonary Disease, Chronic Obstructive - complications
Thorax - pathology
Treatment Outcome
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Summary:We report a case of intrathoracic malignant peripheral nerve sheath tumor in a 65-year old woman revealed after a few-month history of progressive dyspnea, appetite and body mass loss. The chest magnetic resonance (MR) examination revealed the presence of a large tumor occupying the mediastinum and a major portion of the right hemithorax. The diagnostic tumor sample was obtained by parasternal biopsy in local anesthesia. The surgical resection of the tumor could not be performed due to its excessive size, intrathoracic involvement and bad respiratory reserves of a patient. The chemotherapy and irradiation were performed as palliative measures. The lethal outcome appeared 10 months after the diagnosis was established.
ISSN:1512-8601
2831-0896
1840-4812
2831-090X
DOI:10.17305/bjbms.2010.2681