Impact of Exercise Training on Peak Oxygen Uptake and its Determinants in Heart Failure with Preserved Ejection Fraction

Heart failure with preserved ejection (HFpEF) accounts for over 50 % of all HF cases, and the proportion is higher among women and older individuals. A hallmark feature of HFpEF is dyspnoea on exertion and reduced peak aerobic power (VO ) secondary to central and peripheral abnormalities that result...

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Bibliographic Details
Published in:Cardiac failure review 2016-11, Vol.2 (2), p.95-101
Main Authors: Tucker, Wesley J, Nelson, Michael D, Beaudry, Rhys I, Halle, Martin, Sarma, Satyam, Kitzman, Dalane W, Gerche, Andre La, Haykowksy, Mark J
Format: Article
Language:English
Subjects:
Heart Failure With Preserved Ejection Fraction
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Summary:Heart failure with preserved ejection (HFpEF) accounts for over 50 % of all HF cases, and the proportion is higher among women and older individuals. A hallmark feature of HFpEF is dyspnoea on exertion and reduced peak aerobic power (VO ) secondary to central and peripheral abnormalities that result in reduced oxygen delivery to and/or utilisation by exercising skeletal muscle. The purpose of this brief review is to discuss the role of exercise training to improve VO and the central and peripheral adaptations that reduce symptoms following physical conditioning in patients with HFpEF.
ISSN:2057-7540
2057-7559
DOI:10.15420/cfr.2016:16:2