Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study

Pterygium is a vascularized, invasive transformation on the anterior corneal surface that can be treated by Strontium-/Yttrium90 beta irradiation. Finite element modeling was used to analyze the biomechanical effects governing the treatment, and to help understand clinically observed changes in corn...

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Bibliographic Details
Published in:Sensors (Basel, Switzerland) Switzerland), 2017-05, Vol.17 (6), p.1200
Main Authors: Pajic, Bojan, Aebersold, Daniel M, Eggspuehler, Andreas, Theler, Frederik R, Studer, Harald P
Format: Article
Language:English
Subjects:
Astigmatism
Beta rays
Biomechanical engineering
Biomechanics
Computer simulation
Cornea
Curvature
Strontium
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Summary:Pterygium is a vascularized, invasive transformation on the anterior corneal surface that can be treated by Strontium-/Yttrium90 beta irradiation. Finite element modeling was used to analyze the biomechanical effects governing the treatment, and to help understand clinically observed changes in corneal astigmatism. Results suggested that irradiation-induced pulling forces on the anterior corneal surface can cause astigmatism, as well as central corneal flattening. Finite element modeling of corneal biomechanics closely predicted the postoperative corneal surface (astigmatism error -0.01D; central curvature error -0.16D), and can help in understanding beta irradiation treatment. Numerical simulations have the potential to preoperatively predict corneal shape and function changes, and help to improve corneal treatments.
ISSN:1424-8220
1424-8220
DOI:10.3390/s17061200