Chronic disorders of consciousness

Over the last 20 years, studies have provided greater insight into disorders of consciousness (DOC), also known as altered state of consciousness. Increased brain residual functions have been identified in patients with DOC due to the successful application of novel next-generation imaging technolog...

Full description

Saved in:
Bibliographic Details
Published in:Experimental and therapeutic medicine 2017-08, Vol.14 (2), p.1277-1283
Main Authors: Xie, Qiuyou, Ni, Xiaoxiao, Yu, Ronghao, Li, Yuanqing, Huang, Ruiwang
Format: Article
Language:English
Subjects:
Behavior
Brain research
Care and treatment
Caregivers
Causes of
Communication
Consciousness
Development and progression
Diagnosis
disorders of consciousness
Ethics
Eye movements
Medical imaging
Mental disorders
minimally conscious state
Mortality
Neurosciences
Patients
Physiological aspects
Quality of life
Review
Studies
Trauma
Traumatic brain injury
Unconsciousness
unresponsive wakefulness syndrome
vegetative state
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c512t-460148b8c5f730372eb8fcce73a2acadd0e980b682e940751e34178580a73e7f3
cites cdi_FETCH-LOGICAL-c512t-460148b8c5f730372eb8fcce73a2acadd0e980b682e940751e34178580a73e7f3
container_end_page 1283
container_issue 2
container_start_page 1277
container_title Experimental and therapeutic medicine
container_volume 14
creator Xie, Qiuyou
Ni, Xiaoxiao
Yu, Ronghao
Li, Yuanqing
Huang, Ruiwang
description Over the last 20 years, studies have provided greater insight into disorders of consciousness (DOC), also known as altered state of consciousness. Increased brain residual functions have been identified in patients with DOC due to the successful application of novel next-generation imaging technologies. Many unconscious patients have now been confirmed to retain considerable cognitive functions. It is hoped that greater insight regarding the psychological state of patients may be achieved through the use of functional magnetic resonance imaging and brain-computer interfaces. However, issues surrounding the research and treatment of DOC remain problematic. These include differing opinions on the definition of consciousness, difficulties in diagnosis, assessment, prognosis and/or treatment, and newly emerging ethical, legal and social issues. To overcome these, appropriate care must be offered to patients with DOC by clinicians and families, as DOC patients may now be considered to live in more than just a vegetative state. The present article reviews the controversy surrounding the definition of consciousness and the reliability of novel technologies, prognostic prediction, communication with DOC patients and treatment methods. The ethical and social issues surrounding the treatment of DOC and future perspectives are also considered.
doi_str_mv 10.3892/etm.2017.4639
format article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5526117</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A504177696</galeid><sourcerecordid>A504177696</sourcerecordid><originalsourceid>FETCH-LOGICAL-c512t-460148b8c5f730372eb8fcce73a2acadd0e980b682e940751e34178580a73e7f3</originalsourceid><addsrcrecordid>eNptkcFrHCEUxqUkNGGTY69laQj0Mht1Rn1eAmFJ2sKGXNKzuM6bxDCjW90t9L-Pk90uSYgiiv7ep58fIV8YndWg-QWuhxmnTM0aWetP5JgpzStGmTjYrakGdkROc36ipQnJAMRncsQBGBUAx-Tb_DHF4N209TmmFlOexm7qYsjOx00OmPMJOexsn_F0N0_I75vr-_nPanH349f8alE5wfi6aiRlDSzBiU7VtFYcl9A5h6q23DrbthQ10KUEjrqhSjCsG6ZAALWqRtXVE3K51V1tlgO2DsM62d6skh9s-mei9ebtSfCP5iH-NUJwyZgqAt93Ain-2WBem8Fnh31vAxYvhmmuQWspoaBn79CnuEmh2CuUbrQo4xX1YHs0PnSx3OtGUXMlaHm9kloWavYBNVrGwZefxM6X_TcF1bbApZhzwm7vkVEz5mpKrmbM1Yy5Fv7r64_Z0_9TLMD5FsgrG1rfxrxnru9vK1r6i9AznqOnhA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1994959498</pqid></control><display><type>article</type><title>Chronic disorders of consciousness</title><source>Open Access: PubMed Central</source><creator>Xie, Qiuyou ; Ni, Xiaoxiao ; Yu, Ronghao ; Li, Yuanqing ; Huang, Ruiwang</creator><creatorcontrib>Xie, Qiuyou ; Ni, Xiaoxiao ; Yu, Ronghao ; Li, Yuanqing ; Huang, Ruiwang</creatorcontrib><description>Over the last 20 years, studies have provided greater insight into disorders of consciousness (DOC), also known as altered state of consciousness. Increased brain residual functions have been identified in patients with DOC due to the successful application of novel next-generation imaging technologies. Many unconscious patients have now been confirmed to retain considerable cognitive functions. It is hoped that greater insight regarding the psychological state of patients may be achieved through the use of functional magnetic resonance imaging and brain-computer interfaces. However, issues surrounding the research and treatment of DOC remain problematic. These include differing opinions on the definition of consciousness, difficulties in diagnosis, assessment, prognosis and/or treatment, and newly emerging ethical, legal and social issues. To overcome these, appropriate care must be offered to patients with DOC by clinicians and families, as DOC patients may now be considered to live in more than just a vegetative state. The present article reviews the controversy surrounding the definition of consciousness and the reliability of novel technologies, prognostic prediction, communication with DOC patients and treatment methods. The ethical and social issues surrounding the treatment of DOC and future perspectives are also considered.</description><identifier>ISSN: 1792-0981</identifier><identifier>EISSN: 1792-1015</identifier><identifier>DOI: 10.3892/etm.2017.4639</identifier><identifier>PMID: 28810588</identifier><language>eng</language><publisher>Greece: D.A. Spandidos</publisher><subject>Behavior ; Brain research ; Care and treatment ; Caregivers ; Causes of ; Communication ; Consciousness ; Development and progression ; Diagnosis ; disorders of consciousness ; Ethics ; Eye movements ; Medical imaging ; Mental disorders ; minimally conscious state ; Mortality ; Neurosciences ; Patients ; Physiological aspects ; Quality of life ; Review ; Studies ; Trauma ; Traumatic brain injury ; Unconsciousness ; unresponsive wakefulness syndrome ; vegetative state</subject><ispartof>Experimental and therapeutic medicine, 2017-08, Vol.14 (2), p.1277-1283</ispartof><rights>Copyright © 2017, Spandidos Publications</rights><rights>COPYRIGHT 2017 Spandidos Publications</rights><rights>Copyright Spandidos Publications UK Ltd. 2017</rights><rights>Copyright © 2017, Spandidos Publications 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c512t-460148b8c5f730372eb8fcce73a2acadd0e980b682e940751e34178580a73e7f3</citedby><cites>FETCH-LOGICAL-c512t-460148b8c5f730372eb8fcce73a2acadd0e980b682e940751e34178580a73e7f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526117/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526117/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28810588$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xie, Qiuyou</creatorcontrib><creatorcontrib>Ni, Xiaoxiao</creatorcontrib><creatorcontrib>Yu, Ronghao</creatorcontrib><creatorcontrib>Li, Yuanqing</creatorcontrib><creatorcontrib>Huang, Ruiwang</creatorcontrib><title>Chronic disorders of consciousness</title><title>Experimental and therapeutic medicine</title><addtitle>Exp Ther Med</addtitle><description>Over the last 20 years, studies have provided greater insight into disorders of consciousness (DOC), also known as altered state of consciousness. Increased brain residual functions have been identified in patients with DOC due to the successful application of novel next-generation imaging technologies. Many unconscious patients have now been confirmed to retain considerable cognitive functions. It is hoped that greater insight regarding the psychological state of patients may be achieved through the use of functional magnetic resonance imaging and brain-computer interfaces. However, issues surrounding the research and treatment of DOC remain problematic. These include differing opinions on the definition of consciousness, difficulties in diagnosis, assessment, prognosis and/or treatment, and newly emerging ethical, legal and social issues. To overcome these, appropriate care must be offered to patients with DOC by clinicians and families, as DOC patients may now be considered to live in more than just a vegetative state. The present article reviews the controversy surrounding the definition of consciousness and the reliability of novel technologies, prognostic prediction, communication with DOC patients and treatment methods. The ethical and social issues surrounding the treatment of DOC and future perspectives are also considered.</description><subject>Behavior</subject><subject>Brain research</subject><subject>Care and treatment</subject><subject>Caregivers</subject><subject>Causes of</subject><subject>Communication</subject><subject>Consciousness</subject><subject>Development and progression</subject><subject>Diagnosis</subject><subject>disorders of consciousness</subject><subject>Ethics</subject><subject>Eye movements</subject><subject>Medical imaging</subject><subject>Mental disorders</subject><subject>minimally conscious state</subject><subject>Mortality</subject><subject>Neurosciences</subject><subject>Patients</subject><subject>Physiological aspects</subject><subject>Quality of life</subject><subject>Review</subject><subject>Studies</subject><subject>Trauma</subject><subject>Traumatic brain injury</subject><subject>Unconsciousness</subject><subject>unresponsive wakefulness syndrome</subject><subject>vegetative state</subject><issn>1792-0981</issn><issn>1792-1015</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNptkcFrHCEUxqUkNGGTY69laQj0Mht1Rn1eAmFJ2sKGXNKzuM6bxDCjW90t9L-Pk90uSYgiiv7ep58fIV8YndWg-QWuhxmnTM0aWetP5JgpzStGmTjYrakGdkROc36ipQnJAMRncsQBGBUAx-Tb_DHF4N209TmmFlOexm7qYsjOx00OmPMJOexsn_F0N0_I75vr-_nPanH349f8alE5wfi6aiRlDSzBiU7VtFYcl9A5h6q23DrbthQ10KUEjrqhSjCsG6ZAALWqRtXVE3K51V1tlgO2DsM62d6skh9s-mei9ebtSfCP5iH-NUJwyZgqAt93Ain-2WBem8Fnh31vAxYvhmmuQWspoaBn79CnuEmh2CuUbrQo4xX1YHs0PnSx3OtGUXMlaHm9kloWavYBNVrGwZefxM6X_TcF1bbApZhzwm7vkVEz5mpKrmbM1Yy5Fv7r64_Z0_9TLMD5FsgrG1rfxrxnru9vK1r6i9AznqOnhA</recordid><startdate>20170801</startdate><enddate>20170801</enddate><creator>Xie, Qiuyou</creator><creator>Ni, Xiaoxiao</creator><creator>Yu, Ronghao</creator><creator>Li, Yuanqing</creator><creator>Huang, Ruiwang</creator><general>D.A. Spandidos</general><general>Spandidos Publications</general><general>Spandidos Publications UK Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170801</creationdate><title>Chronic disorders of consciousness</title><author>Xie, Qiuyou ; Ni, Xiaoxiao ; Yu, Ronghao ; Li, Yuanqing ; Huang, Ruiwang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c512t-460148b8c5f730372eb8fcce73a2acadd0e980b682e940751e34178580a73e7f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Behavior</topic><topic>Brain research</topic><topic>Care and treatment</topic><topic>Caregivers</topic><topic>Causes of</topic><topic>Communication</topic><topic>Consciousness</topic><topic>Development and progression</topic><topic>Diagnosis</topic><topic>disorders of consciousness</topic><topic>Ethics</topic><topic>Eye movements</topic><topic>Medical imaging</topic><topic>Mental disorders</topic><topic>minimally conscious state</topic><topic>Mortality</topic><topic>Neurosciences</topic><topic>Patients</topic><topic>Physiological aspects</topic><topic>Quality of life</topic><topic>Review</topic><topic>Studies</topic><topic>Trauma</topic><topic>Traumatic brain injury</topic><topic>Unconsciousness</topic><topic>unresponsive wakefulness syndrome</topic><topic>vegetative state</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xie, Qiuyou</creatorcontrib><creatorcontrib>Ni, Xiaoxiao</creatorcontrib><creatorcontrib>Yu, Ronghao</creatorcontrib><creatorcontrib>Li, Yuanqing</creatorcontrib><creatorcontrib>Huang, Ruiwang</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database (ProQuest)</collection><collection>Health &amp; Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>British Nursing Database</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Experimental and therapeutic medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xie, Qiuyou</au><au>Ni, Xiaoxiao</au><au>Yu, Ronghao</au><au>Li, Yuanqing</au><au>Huang, Ruiwang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chronic disorders of consciousness</atitle><jtitle>Experimental and therapeutic medicine</jtitle><addtitle>Exp Ther Med</addtitle><date>2017-08-01</date><risdate>2017</risdate><volume>14</volume><issue>2</issue><spage>1277</spage><epage>1283</epage><pages>1277-1283</pages><issn>1792-0981</issn><eissn>1792-1015</eissn><abstract>Over the last 20 years, studies have provided greater insight into disorders of consciousness (DOC), also known as altered state of consciousness. Increased brain residual functions have been identified in patients with DOC due to the successful application of novel next-generation imaging technologies. Many unconscious patients have now been confirmed to retain considerable cognitive functions. It is hoped that greater insight regarding the psychological state of patients may be achieved through the use of functional magnetic resonance imaging and brain-computer interfaces. However, issues surrounding the research and treatment of DOC remain problematic. These include differing opinions on the definition of consciousness, difficulties in diagnosis, assessment, prognosis and/or treatment, and newly emerging ethical, legal and social issues. To overcome these, appropriate care must be offered to patients with DOC by clinicians and families, as DOC patients may now be considered to live in more than just a vegetative state. The present article reviews the controversy surrounding the definition of consciousness and the reliability of novel technologies, prognostic prediction, communication with DOC patients and treatment methods. The ethical and social issues surrounding the treatment of DOC and future perspectives are also considered.</abstract><cop>Greece</cop><pub>D.A. Spandidos</pub><pmid>28810588</pmid><doi>10.3892/etm.2017.4639</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1792-0981
ispartof Experimental and therapeutic medicine, 2017-08, Vol.14 (2), p.1277-1283
issn 1792-0981
1792-1015
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5526117
source Open Access: PubMed Central
subjects Behavior
Brain research
Care and treatment
Caregivers
Causes of
Communication
Consciousness
Development and progression
Diagnosis
disorders of consciousness
Ethics
Eye movements
Medical imaging
Mental disorders
minimally conscious state
Mortality
Neurosciences
Patients
Physiological aspects
Quality of life
Review
Studies
Trauma
Traumatic brain injury
Unconsciousness
unresponsive wakefulness syndrome
vegetative state
title Chronic disorders of consciousness
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T00%3A03%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Chronic%20disorders%20of%20consciousness&rft.jtitle=Experimental%20and%20therapeutic%20medicine&rft.au=Xie,%20Qiuyou&rft.date=2017-08-01&rft.volume=14&rft.issue=2&rft.spage=1277&rft.epage=1283&rft.pages=1277-1283&rft.issn=1792-0981&rft.eissn=1792-1015&rft_id=info:doi/10.3892/etm.2017.4639&rft_dat=%3Cgale_pubme%3EA504177696%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c512t-460148b8c5f730372eb8fcce73a2acadd0e980b682e940751e34178580a73e7f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1994959498&rft_id=info:pmid/28810588&rft_galeid=A504177696&rfr_iscdi=true