Clinical application value of 3.0T MR diffusion tensor imaging in grade diagnosis of gliomas

The clinical value of MR diffusion tensor imaging (DTI) in grade diagnosis of gliomas was investigated. A total of 31 patients with glioma were administered 3.0T MR convention and DTI examination, with quantitative measurement of anisotropy coefficient fractional anisotropy (FA) and apparent dispers...

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Bibliographic Details
Published in:Oncology letters 2017-08, Vol.14 (2), p.2009-2014
Main Authors: Shan, Wei, Wang, Xing-Long
Format: Article
Language:English
Subjects:
Anisotropy
Brain cancer
Diagnosis
diffusion tensor imaging
Glioma
Gliomas
Magnetic resonance imaging
Medical diagnosis
Methods
MR dynamic contrast-enhanced scan
Nervous system
Oncology
pathology
Software
Standard deviation
Statistical analysis
Tumors
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Summary:The clinical value of MR diffusion tensor imaging (DTI) in grade diagnosis of gliomas was investigated. A total of 31 patients with glioma were administered 3.0T MR convention and DTI examination, with quantitative measurement of anisotropy coefficient fractional anisotropy (FA) and apparent dispersion coefficient (ADC) value, and the comparison of quantitative parameters of glioma between low- and high-grade, which was detected by Mann-Whitney U test. The receiver operation characteristic (ROC) curve was drawn to take the value of ADC and FA in tumor ROI as a critical point, to calculate the area under the curve and to confirm the diagnosis threshold value and evaluate its diagnostic efficiency. The FA value of 14 low-grade glioma cases was 139.4±81.3, with an ADC value of (1.36±0.21) ×10−3 mm2/sec. The FA value of 17 high-grade glioma cases was 103.1±41.5, with ADC value of (1.09±0.28)−3 mm2/sec; the difference between the two groups was statistically significant (P
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2017.6378