Segmental portal/superior mesenteric vein resection and reconstruction with the iliac vein after pancreatoduodenectomy

• Published in: Journal of international medical research 2016-12, Vol.44 (6), p.1339-1348
• Main Authors: Zhao, Xin, Li, Li-xin, Fan, Hua, Kou, Jian-tao, Li, Xian-liang, Lang, Ren, He, Qiang
• Format: Article
• Language: English
• Subjects: Adenocarcinoma - blood supply; Adenocarcinoma - mortality; Adenocarcinoma - pathology; Adenocarcinoma - surgery; Aged; Duodenum - blood supply; Duodenum - pathology; Duodenum - surgery; Female; Humans; Iliac Vein - transplantation; Male; Mesenteric Veins - pathology; Mesenteric Veins - surgery; Middle Aged; Operative Time; Pancreas - blood supply; Pancreas - pathology; Pancreas - surgery; Pancreatic Neoplasms - blood supply; Pancreatic Neoplasms - mortality; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - surgery; Pancreaticoduodenectomy; Portal Vein - pathology; Portal Vein - surgery; Research Reports; Retrospective Studies; Survival Analysis
• ISSN: 0300-0605; 1473-2300
• DOI: 10.1177/0300060516665708

Objective The results of segmental venous resection (VR) combined with pancreatoduodenectomy (PD) are controversial but may be promising. Few studies have described reconstruction of the portal/superior mesenteric vein (PV/SMV) with the iliac vein harvested from donation after cardiac death (DCD). Methods From January 2014 to April 2016, PD combined with segmental excision of the PV/SMV (VR group) was performed in 21 patients with adenocarcinoma of the head of the pancreas (ADHP). The authors established a new technique of venous reconstruction using the iliac vein from DCD and analysed patients’ long-term survival. Results The tumour dimensions and tumour staging were greater and the operation time was longer in the VR than PD group; however, no differences in the resection degree, blood loss, complications, reoperation rate, or mortality rate were found. The median survival was similar between the VR and PD groups. The long-term patency of the donor iliac vein was 90%. The degree of resection was a strong predictor of long-term survival. Conclusion Segmental PV/SMV resection combined with PD is applicable to selective patients with venous invasion by ADHP if R0 resection has probably been achieved. An iliac vein obtained by DCD provides an effective graft for venous reconstruction.