Age-Related Periodontitis and Alveolar Bone Loss in Rice Rats

Highlights • Rice rats fed a standard diet developed periodontitis (PD) by age 30 wks. • A high sucrose and casein (H-SC) diet accelerated the development of moderate/severe PD. • switching to STD diet does not halt/reverse the periodontitis induced by a H-SC diet. • The rice rat is a good model to...

Full description

Saved in:
Bibliographic Details
Published in:Archives of oral biology 2017-01, Vol.73, p.193-205
Main Authors: Aguirre, J.I, Akhter, M.P, Neuville, K.G, Trcalek, C.R, Leeper, A.M, Williams, A.A, Rivera, M, Kesavalu, L, Ke, H.Z, Liu, M, Kimmel, D.B
Format: Article
Language:English
Subjects:
Advanced Basic Science
Alveolar Bone Loss - blood
Alveolar Bone Loss - etiology
Alveolar Bone Loss - pathology
Alveolar crest height
Alveolar Process - anatomy & histology
Alveolar Process - diagnostic imaging
Alveolar Process - pathology
Animal Feed
Animals
Blood Glucose - metabolism
Body Weight
Cholesterol - blood
Dentistry
Diet
Dietary Sucrose - administration & dosage
Dietary Sucrose - adverse effects
Disease Models, Animal
High sucrose-casein diet
Insulin - blood
Male
Mandible
Maxilla
MicroCT
Osteoporosis - blood
Osteoporosis - etiology
Osteoporosis - pathology
Periodontitis - blood
Periodontitis - etiology
Periodontitis - pathology
Random Allocation
Rats
Sigmodontinae
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Rice rats fed a standard diet developed periodontitis (PD) by age 30 wks. • A high sucrose and casein (H-SC) diet accelerated the development of moderate/severe PD. • switching to STD diet does not halt/reverse the periodontitis induced by a H-SC diet. • The rice rat is a good model to study pathogenesis, prevention and treatment of PD.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2016.10.018