Levofloxacin Use in the Neonate: A Case Series

We report 6 cases of intravenous levofloxacin use to treat multidrug-resistant nosocomial respiratory infections in neonates with a postmenstrual age ranging from 27 to 42 weeks. Because of a lack of neonatal-specific information for levofloxacin, the usual pediatric dosage (10 mg/kg per dose every...

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Bibliographic Details
Published in:The journal of pediatric pharmacology and therapeutics 2017-07, Vol.22 (4), p.304-313
Main Authors: Newby, Brandi D, Timberlake, Kathryn E, Lepp, Lyndsay M, Mihic, Tamara, Dersch-Mills, Deonne A
Format: Article
Language:English
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Case Report
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Summary:We report 6 cases of intravenous levofloxacin use to treat multidrug-resistant nosocomial respiratory infections in neonates with a postmenstrual age ranging from 27 to 42 weeks. Because of a lack of neonatal-specific information for levofloxacin, the usual pediatric dosage (10 mg/kg per dose every 12 hours) was used in these patients. Clinical cure occurred in 5 of the 6 patients. Only minimal short-term adverse effects were noted.
ISSN:1551-6776
2331-348X
DOI:10.5863/1551-6776-22.4.304