Peri-operative factors predisposing to pharyngocutaneous fistula after total laryngectomy: analysis of a large multi-institutional patient cohort

Pharyngocutaneous fistula (PCF) is a problematic complication following total laryngectomy. Disagreement remains regarding predisposing factors. This study examines perioperative factors predicting PCF following total laryngectomy using a large multicenter data registry. Retrospective cohort analysi...

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Bibliographic Details
Published in:Journal of otolaryngology-head and neck surgery 2017-08, Vol.46 (1), p.54-54
Main Authors: Lebo, Nicole L, Caulley, Lisa, Alsaffar, Hussain, Corsten, Martin J, Johnson-Obaseki, Stephanie
Format: Article
Language:English
Subjects:
Aged
Analysis
Care and treatment
Causality
Cohort Studies
Complications and side effects
Confidence Intervals
Cutaneous Fistula - epidemiology
Cutaneous Fistula - etiology
Cutaneous Fistula - surgery
Databases, Factual
Diagnosis
Female
Fistulas
Humans
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - surgery
Laryngectomy
Laryngectomy - adverse effects
Laryngectomy - methods
Male
Middle Aged
Multivariate Analysis
Odds Ratio
Original
Patient outcomes
Perioperative Period
Pharyngeal Diseases - epidemiology
Pharyngeal Diseases - pathology
Postoperative Complications - epidemiology
Postoperative Complications - pathology
Predictive Value of Tests
Prognosis
Reconstructive Surgical Procedures - methods
Retrospective Studies
Risk Assessment
Risk factors
Treatment Outcome
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Description
Summary:Pharyngocutaneous fistula (PCF) is a problematic complication following total laryngectomy. Disagreement remains regarding predisposing factors. This study examines perioperative factors predicting PCF following total laryngectomy using a large multicenter data registry. Retrospective cohort analysis was performed using patients undergoing total laryngectomy in the ACS-NSQIP database for 2006-2014. Sub-analysis was performed based on reconstruction type. Outcome of interest was PCF development within 30 days. Multivariate analysis of 971 patients was performed. Three variables showed statistical significance in predicting PCF: wound classification of 3 and 4 vs. 1-2 (OR 6.42 P 
ISSN:1916-0216
1916-0208
1916-0216
DOI:10.1186/s40463-017-0233-z